I would suggest a referral to a pulmonologist. Many things can elevate a d-dimer, but one thing I would make sure is a chronic pulmonary embolus. A CT pulmonary
angiogramArteriogram
Cerebral angiography
Cholecystitis, cholangiogram
Coronary angiography
Gallstones, cholangiogram
Hemangioma - angiogram
Lymphangiogram
Percutaneous transhepatic cholangiogram
Renal arteriography or ventilation/perfusion scan would be reasonable tests to evaluate for this.
A CT scan, including high-resolution CT scan, should be performed, in addition to pulmonary function tests - if they haven't been performed already.
A more specialized test would be
cardiopulmonaryCpr
Cpr - adult exercise testing.
CardiopulmonaryCpr
Cpr - adult exercise testing is indicated when the etiology of a patient's shortness of
breathBreath alcohol test
Breath holding spell
Breath odor remains unclear after the initial evaluation described above, or when it seems out of proportion to the severity of the patient's known cardiac or pulmonary disease. This test can determine whether the shortness of breath is coming from the heart or lungs.
Another heart test would be a blood test known as a B-naturetic peptide. Elevated levels of this would suggest a cardiac source.
In any case, I would suggest a referral to a pulmonologist to discuss the possibility of these tests. Any academic medical center (i.e. near a major city like Detroid) would be appropriate.
Followup with your personal physician is essential.
This answer is not intended as and does not substitute for medical advice - the information presented is for patient education only. Please see your personal physician for further evaluation of your individual case.
Thanks,
Kevin, M.D.