Vaginal cancer occurs in 2 percent of cancer cases of the female genital tract. The majority of patients with vaginal carcinoma present with vaginal bleeding, either postmenopausal or postcoital. Other symptoms include a watery, blood-tinged, or malodorous vaginal discharge, vaginal mass, urinary symptoms (eg, frequency, dysuria, hematuria), or gastrointestinal complaints (eg, tenesmus, constipation, melena).
The diagnosis of vaginal carcinoma can be difficult. Papanicolaou (Pap) smear may detect malignant cells; 20 percent of vaginal tumors are detected incidentally as a result of cytologic screening for cervical cancer.
Definitive diagnosis is accomplished by biopsy of the suspected lesion, which may appear as a mass, a plaque, or an ulcer. If a lesion is not visualized in the presence of abnormal cytologic results, colposcopy of the cervix should be considered.
I would suggest a biopsy if the PAP smear returns negative.
Followup with your personal physician is essential.
This answer is not intended as and does not substitute for medical advice - the information presented is for patient education only. Please see your personal physician for further evaluation of your individual case.
Thanks,
Kevin, M.D.
Bibliography:
Elkas et al. Vaginal cancer. UptoDate, 2003.