Fertility / Infertility / IVF Community
Clomid, Metmorphin, HCG injection
About This Community:

This patient support community is for discussions relating to genetic testing, in-vitro fertilization (IVF), ovulation, pregnancy reduction post-IVF, relationship issues, and sperm count and quality.

If you are trying to conceive for less than one year, please visit our Pregnancy: Trying to Conceive (TTC) Community

Font Size:
A
A
A
Background:
Blank
Blank
Blank
Blank Blank

Clomid, Metmorphin, HCG injection

Hello All,
I am new to this website. My endocronlogist put me on Clomid 50mg and Metmorphin 150mg. I had one mature follicle(17mm). But I was not pregnant that month(Sep 2006), then our next cycle she increased the clomid dosage to 100mg. I still had one mature follicle(24.5mm). I had my IUI done in that cycle. First week after the IUI, the progestrone level was 21.5 and my estrogen level was 200. But still no luck.
I am having 30 day cycle now that I started taking Clomid. I use to have irregular periods before that.

I got my last period on Nov 10th, and I started taking Clomid from Day 4. My doctor suggested that when I will start to ovulate, then I shd take my HCG injection. I want to know, what is use of HCG injection? And are there any side effects?
With Clomid, I notice some discomfort in the ovaries and sometimes hotflashes. But nothing drastically painful.
I don';t understand, why despite everything being so timed, monitored through blood work and Ultra sound, nothing worked so far.

Any suggestions? I am feeling very worried and restless.

Thanks,
Akapoor
Related Discussions
29 Comments Post a Comment
Blank
93654_tn?1247502934
The hcg shot is also called a trigger shot, and it's just one more way to ensure that ovualtion takes place. I don't recall any side effects with the hcg injections, but you don't want to test too soon after the shot, because the residual hcg can cause a postitive result. What tests has your RE done so far on you?
Blank
Avatar_n_tn
I have take the HCG shot on day 12 then we do IUI on day 13. I have noticed with the shot that I get a really bad headache and get sort of sick to my stomach. Hope things work for you. I have to give myself HCG on Sunday morning (3am), I have never had to give it to myself before and am a little scared. My DH can't stand needles so I am on my own. Good luck to you.
Blank
93654_tn?1247502934
When I had to give my own injection, I used an ice bag on my upper thigh, and took the shot there. That way, it was nice and numb, and I could sit down and see what I was doing.
Blank
Avatar_n_tn
How successful is IUI?
Younger women usually have higher rates of success compared to women over age 35, but the average success rate for IUI ranges from 10-20% in one cycle. With IUI, as with other methods of artificial insemination, the success is dependent on the health of the sperm and the woman's body.

This will be my second sound of IUI. We have to use a donor because my DH's (dear husband)little guys are few and slow.
Blank
Avatar_n_tn
Thanks all for your quick responses. My RE has done all blood tests etc. But as for the cycle, they do my UltraSound(US) and blood work on day 3, day 10. Then depending on my day 10 results they call me either on day 12 or day 13th for blood work and US.
For the past 2 cycles, I noticed that my ovulation is usually on day 15/16. Since for last cycle, I didnt take HCG, they asked me to come on 25th Oct(first day of my cycle was on 10th Oct) for the IUI.

Yea, I am also very scared of needles. I don't think I can inject that shot myself.

Btw, what does DH and bd mean? I have seen this abreviation in many places?

Also, do the chance of getting pregnant increase from cycle to cycle( since one is usually clomid regularly)?
Also, what are the chances of getting pregnant with IUI?

Please let me know. Thanks for all  your wishes. I need them.

Regards,
Akapoor
Blank
Avatar_n_tn
Hi Everyone,

Thanks for your responses. I had my day 10 test today. Well, the doctor said that in u/s I have few little follicles. None dominant so far. And in the blood work, my estrogen level was little low. She asked me to come back on day 12, i.e Tuesday for u/s and blood work again. I am so confused. Can some one please tell me if the clomid success rates increase with each cycle?

Thanks,
Akapoor
Blank
Avatar_n_tn
dh= dear husband (or damn husband... depending on mood :)
bd= baby dance (you know, the one you and dh do to MAKE a baby)
Blank
Avatar_n_tn
I'm using OPK's to monitor my LH surge, then I'm supposed to give myself an HCG injection. I'm on Letrozole cd 3- cd7. Anyone else had experience with this they could share. I'm afraid I won't do the injection on the right day... Dr has me doing it myself since we live so far away...

Insight please... I'm on cd 11 tomorrow (9.18.2007)

Thanks everyone

baby dust********

hollie
Blank
Avatar_f_tn
how big are the needles you have to take the hcg with? what guage size also how many cc is equal to 125 iu.  also my husband is in the navy so the doctors want to know where therre is research that hcg helps fertility please let me know of a reputable website for research thanks
Blank
Avatar_n_tn
I am on my third IUI with doing follistim shots to produce follicles and then doing an hcg shot to induce ovulation.  I order both from IVP (a pharmaceutical company) that my fertility dr. hooked me up with.  The hcg shot really is no big deal - it came already pre-filled with the correct dosage and my dr. told me the exact time to inject myself (based upon when the artificial insemination was going to be done the following morning, and again 24 hrs. later).  The shots don't really hurt, besides the "pricking" of the needle.  I have looked up lots of info. on hcg and have many friends who have done IUI and in vitro fertilitization, and all have been successful so far.  I have done lots of research and have an awesome fertility dr.; so if you don't, please feel free to ask me any questions and I can try to help you out!  good luck!
Blank
418703_tn?1308828820
hi everyone im fairly new to all this as ive only just been diagnosed with pcos.
its thrown me back a bit as both me and my boyfriend have been trying for a baby for the last 2 years and had no luck so far
the doctor is going to perscribe me metformin
im trying to do some research on the drug and having difficulty
can anyone give me some advice about metformin and what it does please?
i need all the help i can get
thanks
xxxclairexxx
Blank
325477_tn?1250554909
Hi, my RE just prescribed Metformin for me as well, As far as I understand, Metformin reduced insulin in your body and makes your ovaries produce less Follicles and cysts..I had 30 in each ovary so metformin supposedly suppose to reduce it so ovaries can produce less follicles and less cysts...
after 1 cycle of metformin, you will have blood work done to see if your liver functions properly ( as Metformin can give an implact on your liver), and if it is ok, then for next cycle,  you will be given Clomid with Metformin ( i think), to induce Ovulation...
That's where I stand so far!
Good luck! Feel free to ask any questions!
Anya.
Blank
418703_tn?1308828820
hi, thanks for your reply i will keep you updated xx
i am only 19 and my bf is 22 do you think we are  too young to settle down and start a family??
Good Luck 2 u 2 Hope everything goes well!!!
Blank
325477_tn?1250554909
I think you are lucky that you are young but if you want to marry  your bf, then you can start the treatment..it might take a while before you actually get Ovulation and pregnant...if you are not ready for a baby yet, then you should at least get regular Ovulation and find out what drugs work for you....
I wanted to go in when I was 19 but my OBGYN was not giving me any diagnos and I waited..now I am 24...
Anyway, it s up to you, but earlier you start, the better for you!
Anya.
Blank
415687_tn?1228749875
I'm hearing this for the first time,(as Metformin can give an implact on your liver )pls can you explain a bit more. My dr put me  on metformin since over 3months ago and never talked about having bloodwork done.

thanks

lili
Blank
418703_tn?1308828820
hi, can someone explain to me how you know when your most fertile or when the best time to concieve (conceive) is please i don't understand all this yet and the gyne won't take the time out to discuss. wed 30th jan 07 i was prescribed a 5 day course of Medroxyprogesterone 10mg 3 times a day but that was just to bring on a period (it started today sooooo painful) as i havent had one since 2nd dec 2006 thats how i found out i have pcos. i feel silly i have pcos and don't fully understand it!!!

xxclairexx
Blank
Avatar_f_tn
hello all,
i was wondering if anyone here has taken or heard of femara? if so, what are the side effects of this drug? i only saw that it is used for women with breast cancer.
i've been on it for 10 days and just had hcg shot yesterday,have to wait for day 20 to do hpt.
Blank
Avatar_f_tn
hello all,
i was wondering if anyone here has taken or heard of femara? if so, what are the side effects of this drug? i only saw that it is used for women with breast cancer.
i've been on it for 10 days and just had hcg shot yesterday,have to wait for day 20 to do hpt.
Blank
330481_tn?1309491843
In response to a couple of the posts. I have PCOS and wasn't ovulating on my own. I did clomid for 3 months on my own and didn't O until I hit 1oomg (1 egg). When I did 150mg, I o'ed 2 eggs. Still didn't get pregnant. Went to RE, went on menopur shots, clomid (50mg) and ovidrel (hcg) shot. O'ed 1 egg and got pregnant (just miscarried at 6 weeks 5 days). I also added metformin a few cycles ago and it helped me O on my own just by being on it by itself - think only one egg - but I didn't get pregnant with it. Hubby and I are going to try to do just the metformin for the next cycle or two before we go back to the menopur shots, clomid and hcg shot. But i truly think the menopur, clomid, and HCG shot was a miracle combo. Even though we lost our munchkin, we still got preggo right away on it. We also just did timed babydancing - no IUI (DH sperm is fine).

To answer the other question, I LOVE my clearblue fertility monitor and charting!! After I had the HCG shot, it is always thought that you O 36 hrs later. Nope! I O'ed almost 4 days later!!! If i hadn't been using that fertility monitor when I was I would have thought to stop BDing but my monitor said peak fertility and we BDed for 3 days after the shot and got preggo. I told Dh, "that's what the monitor says - so lets do it some more" and we got preggo.

So, a great combo to start off with (if you want to avoid alot of drugs and your cycles are normal) try charting and the clearblu fertility monitor. You can get the monitor on ebay for around 100 bucks.

Good Luck and super sticky baby dust (SSBD) to all!!
Blank
Avatar_f_tn
Hello all,

its been a while since anyone has posted concerning the fertility drugs. i recently had my clomid increased to 100 mg, taking metforomin 150 mg, and recently had my first hcg injection (which i injected myself and wasn't as bad as i thought it would be) but the effects made me feel like i had morning sickness.


anyway, this is my second clomid cycle and i am concerned about it not being a positive result. i've been diagnosed w/ pcos over 7 years ago, am 33 and just recently started trying to get pregnant w/ my DH.

right now i just don't want to get discouraged so any words of encouragement would be appreciated.
Blank
Avatar_f_tn
Don't be discouraged. I also have PCOS and am this time around on my 2nd round of Clomid. I am on 100 mg days 3-7 and on 1000 mg glucophage. I go today for my Ultra sound to see if I have any mature follies. :O)
Good luck, I'll check back and see how your doing. I also belong to a wonderful thread that is "lets keep this thread rollin, Cycle Buddied # 8"
You are more than welcome, there are several women going through the same thing.
Hope to see you there.
Blank
Avatar_n_tn
do you have to have a menstrual to concieve (conceive) or is that what the injections do for you without the bleeding? Sorry to sound so dumb but as i have seen its easier to ask people who are going through this. I have been prescribed hcg and menopur.  My problem is that i almost never have my period. any suggestions?
Blank
Avatar_f_tn
hi i was just wondering if anyone else is going through what i am at this very moment.  we've been ttc for 3 years.  we've tried clomid know this month we are trying clomid with the hcg shot(that is if everything looks right when i have my ultrasound on the 29.  
anyone else going through this??
Blank
Avatar_f_tn
when do you inject the HcG if you want to increase your chance of ovuluation when you're placed on Clomid and at what dosage and for how long?
Blank
Avatar_f_tn
Hey heatherlynn40

I am going through the same phase too. I just had my hcg shot today in the morning. This is my first round of Clomid 100mg and my body reacted slow to it. Its my day 18 and today the follicles were 24mm and hence I got the shot. They need to see atleast one follicle above 20mm for a hcg shot.
I will have my IUI tomorrow. Fingers crossed :) I am very excited and hope things go fine in the first round itself. Good luck to you too.  
Blank
Avatar_f_tn
Hey tingding,

hcg is usually given on the day you turn positive on OPK. Otherwise, if you are being followed up with ultrasound regularly, you will be given a shot if you have a follicle of atleast 20mm. Hope that explanation helps.
Blank
Avatar_m_tn
Hello all. I also have pcos and have been on Metphormin for about a year now. I have been on clomid for about 4 months and still no luck. I had my first hcg shot in August and it didnt work. I had the insemination done last month and it was still negative. I go in for my ultrasound tomorrow and if I have a follicle, they will give me the HCG shot. Any other suggestions that I should be doing to increase our chances?
Blank
Avatar_f_tn
I'll testify soon.
Blank
Avatar_n_tn
will HCG inj definitely lead to ovulation
Blank
Avatar_n_tn
will HCG inj definitely lead to ovulation
Blank
Post a Comment
To
Blank
Weight Tracker
Weight Tracker
Start Tracking Now
Fertility / Infertility / IVF Community Resources
RSS Expert Activity
469720_tn?1388149949
Blank
Abdominal Aortic Aneurysm-treatable... Blank
Oct 04 by Lee Kirksey, MDBlank
242532_tn?1269553979
Blank
The 3 Essentials to Ending Emotiona...
Sep 18 by Roger Gould, M.D.Blank
242532_tn?1269553979
Blank
Control Emotional Eating with this ...
Sep 04 by Roger Gould, M.D.Blank
Top Trying to Conceive Answerers
Avatar_n_tn
Blank
pinkrazrbrd
Avatar_f_tn
Blank
Dragonwings
8319766_tn?1417385636
Blank
tasha0918
corona, NY
Avatar_f_tn
Blank
isha01
Avatar_f_tn
Blank
momz1st
9334757_tn?1418163588
Blank
brittanie_may