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296340 tn?1336164001

Info about Baby Aspirin

Aspirin

When you think of aspirin, you probably associate it with fever or headache relief, or for use as a mild anti-inflammatory. However, new research now shows that aspirin could play an important role in some women who are struggling with infertility. Aspirin is now being offered in conjuction with other medications to help increase the rate of pregnancy in women receiving certain fertility treatments. If you are having trouble conceiving, speak with your reproductive endocrinologist about aspirin therapy for fertility.

What is Aspirin?
Aspirin has been around for just over 100 years. More than 80 billion aspirin tablets are sold every year, typically to help solve minor aches and pains like headaches and muscle strains. Aspirin is actually created from a chemical called acetylsalicylic acid. This chemical works to reduce pain and inflammation by inhibiting the action of Cox-2 enzymes in your body. Cox-2 enzymes produces prostaglandins, special hormones that cause pain. By preventing these Cox-2 enzymes from producing prostaglandins, aspirin can help to relieve your pain.


Aspirin and Infertility
Recently, it has been discovered that aspirin seems to help women experiencing certain types of infertility. In particular, it appears to increase the chances of pregnancy in women who have experienced recurrent spontaneous abortions, or miscarriages.

Antiphospholipid Antibodies and Aspirin
Some women who experience recurrent sponataneous abortions have extremely high levels of antiphospholipid antibodies. These antiphospholipid antibodies can cause your blood to become much thicker than usual, as they cause blood platelets to stick together. This can dramatically increase your risk for developing problematic, or even fatal, blood clots. Many women with increased antiphospholipid antibodies tend to experience multiple miscarriages because blood clots can develop around the placenta, depriving the baby of vital oxygen and nutrients.

How Does Aspirin Help?
Aspirin appears to help thin out the blood in women who are experiencing these problematic blood clots. When given in low doses, aspirin makes your blood platelets less sticky, allowing blood to travel more easily through the placenta to your baby. Asprin is typically given along with Heparin, an anticoagulant medication.

Aspirin Studies
Recently, a number of different studies have been performed on the use of aspirin to increase fertility. Women who had experienced multiple miscarriages and who were undergoing IVF treatment were given low doses of aspirin daily. Subsequent pregnancy rates were then compared to pregnancy rates produced by women who received no aspirin therapy. Surpisingly, more than 45% of those women taking aspirin during treatment became pregnant, while only 28% of those women not taking aspirin were able to conceive.

Recent aspirin studies also show that aspirin may be helpful in increasing pregnancy rates in all women. Aspirin appears to increase the activity of the ovaries, allowing them to release multiple eggs during ovulation. It also appears to increase blood flow to the uterus, allowing for a thicker and healthier uterine lining.

How is Aspirin Taken?
Aspirin therapy is taken orally in small daily doses. Also known as baby aspirin, low dose aspirin therapy contains between 78 and 81 milligrams of acetylsalicylic acid. If you are taking aspirin for infertility you should be under the direct supervision of a licensed health care provider.

Aspirin Side Effects
Aspirin therapy is still being tested for side effects and is currently only available when taken in combination with Heparin. Long-term use of aspirin is not recommended, because it may actually interfere with fertility. Long-term aspirin use appears to prevent a woman's eggs from being released from their follicles, inhibiting ovulation. Aspirin therapy should not be taken by women who are:

allergic to aspirin
experiencing gastric inflammation or bleeding
6 Responses
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1283095 tn?1279472631
Read all the positive results and I will take this for my 5th time around. Thanks. Quick question though. When is aspirin taken? Is it prior to transfer or post transfer. Thank you once again for all the great information you all have posted. Adds a little more positive ways of trying to make it work for the future and create more objectives :o)
Helpful - 0
641304 tn?1434543092
l went through ivf and didnt get pregnant after first fresh embryo transfer.then l got another frozen transfer and they transfered two embryos that didnt implant..so for the third frozen transfer,l read on MH that aspirin works and l tried it and it DID WORK .l am on 9th week pregnant with twins.How long should l continue taking it?l encourage people to take aspirin if they have fertility issues
Helpful - 0
287071 tn?1365192513
I had two miscarriages last spring and with testing over the summer it was discovered that I have a clotting issue - baby aspirin is the treatment.  I'm not 16w5d - I faithfully take my baby aspirin every day!  When the baby is born I'm going to take a picture with a bottle of Bayer and send a thank you letter to them!
Helpful - 0
381606 tn?1242090749
Thank you SO much for this info...very helpful. My doc just suggested I start it so hopefully it will work for me too!


Helpful - 0
Avatar universal
I did it too!!!  I had 2 mc and then took it before conceiving and I took it throughout pregnancy!  I had a little girl in August!  It works!
Helpful - 0
178590 tn?1294176767
it works I took it to get pregnant and am still taking it to keep my little ones snug inside.
Helpful - 0
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