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PLEEASE!!! Help with any knowledge of injections.
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PLEEASE!!! Help with any knowledge of injections.

I am hoping there are people out there just a confused as me.
Ok, I began my journey to IVF on July 24, 2008. I began taking .2cc of Lupron in the morning, and .2cc of Lupron at night. Then 8 days later (Aug 1,08) I began lupron .2cc in morning with Gonal F 300, for two days, Friday and Saturday. I went in Sunday (Aug3) to get my E2 checked. It was 21. The nurse called to tell me I needed to take 450 of Gonal F that evening, and 225 ml of Gonal F until Friday when I go in for more blood work, and an ultrasound. Now with that being said. Is this a good dosage? I have heard I should not over stimualte my ovaries, this could be a reason for miscarriage or failed IVF. Has anyone had ANY experience with this. I am in need of any help. I feel like a drug addict. Poking myself here and there, my fridge looks like a pharmacy, injections, needles, suppositories... Are all these meds necessary. And maybe someone can tell me why it is important to stay in bed after the transfer, will the embryo not attach if you move around.
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216278_tn?1308864682
IVF is a scary, but exciting time - it can also be very overwhelming. It's hard to tell you what is a 'good' dosage - the most important thing is to be monitored constantly.  One of the problems of the meds is that they continue to work even after being taken off of them, so you want to make sure that you are getting b/w done to check the Estradiol levels.  One fear of IVF is overstimulation, but more so in that it evolves to OHSS (Ovarian HyperStimulation Syndrome).  With your levels so low right now, that's not an immediate concern, so try to relax (I know that it's hard).  Keep asking for the numbers of your levels and be involved - it'll help you feel better about the whole thing.

Staying in bed after the transfer is for a couple of reasons (IMHO) - first and foremost, for the emotional well-being of the mother.  Studies were done regarding IUI and found that mothers who were told to get up and leave as soon as the procedure was done were more stressed and concerned that 'it didn't take' than those who were allowed to lay still for half an hour.  Secondly, your body has been through a long and hard journey by the time that the babies are transferred, so it's important to give it an opportunity to just relax and recover!

Hope that helps!   Good luck and SSBD!
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215752_tn?1278008371
This is the  way of IVF that my Re just put me. I just finished the first cycle. I started with bcp for 3 weeks. After that lupron .2cc in the morning for 1 week. Then lupron .1cc in the morning and gonal f 225 for 10 days.I had the same dosage from day one. I don't know that they should change it. Your dosage it'snot a low one. I developed 12 eggs and i have some cysts one both the ovaries and also fluid everywhere so we posponed the trsnfer for a couple of weeks until this situation goes down. OHSS it's not an easy condition so your doctor should be very carefull. My dosage is lower than yours yet my hormones on day 7 were already skyroking. Good luck
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200957_tn?1236140523
What is the Lupron for? I thought this was to keep me from ovulating. The Gonal F is to make follicles right? I have been going through this for so long, everything seems to be running into another. Does anyone know how long the standard time to remain on Lupron or Gonal F is? I go back into the Dr. on Friday for an ultrasound, I assume this is to get a view of how many follicles I have. I also had a cyst. This is why we opted to go straight to IVF instead of IUI. Since I had to take birth control to help dissolve the cyst, we didn't want to waste anytime. I'm 35 and feel like time is slipping by. It is just confusing to me that every doctor seems to have their own cocktail.
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413852_tn?1317312312
Ascott...

It is REALLY frustrating when you don't know what is going on. You should tell your doc you NEED for them to explain the txment to you better. At times...which is really sad...we have to remind these nutjobs that we don't have MD behind our names and we need to understand the procedures & meds a lot better. Everyone is different, thus the different dosages of meds. My dosage was high as well. It just depends on how your body responds to the txment. ;o) The particular tx. you are having is named...I didn't take Lup, but was on a type of tx. that seemed to be going against what we needed to accomplish & became very frustrated. Lup is used to calm your ovaries down so that they don't ov on their own. The GonalF is used to slowly grow the follies. I think that's correct, from what I can remember fr. my last IVF cycle. If the ovaries aren't calmed down, they might cause the body to release them on their own. This way...the ovaries are calm & the GonalF can cause the body to grow (mature them) the follies larger w/o being released. I forget the name of this particular tx.  You can also use goole or "ask.com" & type in the two meds followed by type of infertility protocol. Hope this helps. Hopefully if it is off, someone will come by & make it a little clearer. ;o)

Cheers~
Savanha~~
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Avatar_f_tn
I understand how you feel and IVF is confusing at times - with all the medications, doses and etc.  And every doctor have their own protocol as far as meds go too..  But I think you should also do your part, not that you're not, but if you are in the docotr's office or have an appointment with the doctor, that's where you should ask all your questions.  They like it when you ask and right there and then, you get answers.  If you are not satisfied with what they tell you, you can search online.  As far as meds go, when you buy these medications from pharmacy, they should have leaflets about the meds you get.  It should include the uses or indications, side effects, etc.  If not satisfied or if you want layman's explanation, sometimes you get those online too.  Reading the leaflets of meds, that's how I learned that most of these medications we take or inject are also meds for cancer patients.  That's why also when you experience chest pain, try to call your doctor or don't ignore it because of the medications we get, our hormones are way up and these meds could also case cardiac arrest.  It's scary, I know but when I had chest pain one time, I had ekg and troponin checked just in case.  That's why we also take aspirin.  Anyways, good luck and I hope you can also learn a lot from the people here.
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Avatar_f_tn
Also, with the bed rest, after transfer, you are just allowed to go to the rest room and no other activity since ther fertilized egg is just floating and with bed rest, it will help with implantation.  I even regret just taking 2 days bed rest, although that's what they normally tell you and you can resume regular activities after with the exceptions of no lifting of more than 10 lbs, no jarring, no sex or orgasm and etc, until after your pregnanc y test.  Sometimes it's difficult to really get 2 wks rest but I wished I did....just wanted to be sure but I was back to work after 3 days, just a day work though and i was off for the weekend.  Just be careful with your activities and good luck again.
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Avatar_f_tn
I just started injections this week too, and it is so overwhelming!  My doctor told me about the menopur and the gonal, and the nurse taught my husband and I how to do the injections. When I went to pick everything up at the pharmacy, however, the menopur is now different (no needles, although the nurse showed me how to get everything with a needle - but now it used a Q-cap needleless system to fill the syringe).  And there was progesterone tablets in the bag that my dr. hadn't mentioned at all.  The pharmacist was wonderful, explaining the new packaging and how to use the different ampules, and explaining that the progesterone will be needed later but the dr. wanted me to be prepared and she'll tell me when to start them.  

Beginning injections is scary and very emotional for me already (I had thought the clomid would work and never expected to do injections), so little changes and confusion seems even more overwhelming.  

As for dosages, my dr. said that everyone is different.  She works with many women with pcos like me and with similar issues, but I reacted differently than many of her other patients on Clomid - basically NO reaction in the ovaries at all.  So, my dosages may be higher than another woman who is easily stimulated.  And she explained that with many of these meds, they don't know how each body will react to each dosage until they try it.  So, don't worry if your dosage is different from someone else, because it is tailored to your needs.
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200957_tn?1236140523
Thanks for all the comments. I do ask my RE the questions, sometimes I feel more confused coming out then going in. Before I got to this point, I was looking for another RE. Was not happy with her bedside manner. To hurry hurry for me. He nursing staff is wonderful, the RE however makes me feel like she has been doing this too long. Everything like she has rehearsed it a 100 times.  I swore if I had to do IVF I was not going to have a baby. Just like I said if I turned 35 and was not pregnant I was not going to have a baby. Well I turned 35 in May and began IVF in July. I have been seeing this RE since last year. I stopped in january and February after beign tired of being tired. I mean I have been on baby asprin, folgard, prenatal vit, calcium 2times a day, fiber progestrone suppositories.... now I'm on Lupron, Gonal F, folgard, calcuim.. I have progestrone suppositories growing out of my fridge, I have bagged up medication in my bag for bring to procedure, during procedure, after procedure, after pregnancy.... and the list goes on. When I talk to my doctor I seem to understand everything, sometimes DH walks out hearing something completely different. I just don't feel comfortable and she supposed to be the best in the area. She's in magazines; and GYN/OB's recommend her. At first I thought it was me but no w that I am hearing there are RE's that take time to explain it makes me feel like I should have followed my gut. I just did not want to waste anymore time finding another RE. they are always so booked. At least the good ones. sorry for the run on. Just needed to vent.
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413852_tn?1317312312
Ascot...

I definitely say CHANGE RE's if you must...you have to be confortable. Some people can handle rude bedside manners because of what they are trying to achieve, but I'm the type that if you are nasty or I feel rushed...you don't take time with me...I''m out of there. It seems the more "famous/good" they are, the worse their manners. I had to switch docs as well...he was a TOP doc & in some of the best mags, but he diagnoised me incorrectly & I left him straight way. I completely understand the confusion. I hope it becomes clearer to you the longer you are in tx., which I hope for you isn't very long...pray that you get the sticky dust you long for.

Cheers~
Savanha~~
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Avatar_f_tn
You're going through quite alot and with all the meds it doesn't make it any easier..~~.....if you're uncomfortable now, it's just going to get worse.....the more publicized RE's are just in it for the money ...that's why they advertise all over .....if you're going to someone who has ads in the big pregnancy magazines, you're probably just being treated like a number...and being in the advertising industry, you have to realize if there are articles written about some doctors in the magazines, more likely than not the Doctor wrote it himself ~ look in the Top Doctors magazine...they don't accept articles written by doctors and you can actually follow their recommendations.....dealing with rude people just makes life more difficult than it needs to be...BEST of luck, and hope you are able to feel more comfortable QUICKLY to bring that new life to realization!!!
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