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270512 tn?1333177636

fragmentation

This is our third ivf round, and as usual, our embryos have fragmentation.  We had 17 follicles - 13 eggs - 10 fertilized - 8 went on to division - and all have some sort of fragmentation to them.  The Dr. states that there are 3 that look the best (whatever that means).  The good news is that they all seem to be dividing like they are suppose to.  We have decided to wait to see if any make it to the blastocyst stage.  
Has anyone had fragmentation with good results?  And what the bleep causes the mess?
Thanks to all...
Frustrated in Alaska!
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Avatar universal
Keeping my fingers crossed for you! I did 2 cycles ending up w/ very fragmented embies that didn't make it to blasts, and we opted to not transfer any of them because of the fragmentation and I didn't think I could emotionally deal w/ the wait and the results we were sure to have (neg pt). Retrieved 15 eggs on first cycle and 18 on second w/ all fragmented of the ones that fertilized (don't remember how many actually fertilized, I was so devastated when I went in to be told/shown the results!) We ended up using donor eggs. (I was 34 at the time so very much surprised, plus had a 5 year old conceived on our own). I sure hope your little ones fight and make it!!!
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463339 tn?1207532884
I have not had IVF so I can only speak from the embryology perspective.  Embryos are self correcting this early in development, so the fragmentation is causes by the embryo kicking out the junk or the stuff that doesn't need to be inside the embryo.  So the theory is, the more fragmentation, the more junk the embryo is kicking out, and the less normal the embryo is. But a smal amount of fragmentation is not always abnormal or bad.  Ask your RE for a percentage of fragmentation.  Once the embies reach the blast stage you cannot see the fragmentations anymore.  You are grading based on inner cell mass (which becomes the baby) and the trophectoderm (becomes the placenta.)  Good luck to you@@
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