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Fertility / Infertility  (Expert Forum)
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Clomid 50mg or 100mg?
Questions in the Fertility/Infertility forum are answered by doctors affiliated with USF Health. Topics covered include fertility or infertility issues, egg quality, fertility drugs and side effects, fertility tests, genetic testing, in-vitro fertilization (IVF), ovulation, relationship issues, risk factors, sperm count/quality, and surgery.

Clomid 50mg or 100mg?

by chinup2, Jul 08, 2007 12:00AM
I was on Clomid 50mg from CD 5 to 9. The progesterone level on CD 19 was 2 (US system), but on CD 21, it was 14; and my BBT was high. But I started my period on CD36 and BBT dropped. Last time, my doctor was out of town, so we didn't do the ultrasound. Did I ovulate last round? and if i did ovulate why didn't we conceive? (we did use the OPK and did as my doctor requested). Also the sperm count and post coital test are OK. Should i on Clomid 50mg or increase to 100mg for this round. Thank you.

by Forum-M.D.-SP, Jul 08, 2007 12:00AM
Dear chinup2;

Yes, you did ovulate. With clomid, what sometimes happens is that ovulation is delayed. Generally, if you do not get pregnant, periods start around 11-14 days after ovulation, so the low progesterone on day 19, the high progesterone on day 21, and the period on day 36 all go along with ovulation having occurred somewhere on day 19-20, probably day 19 since progesterone starts to climb a bit around ovulation and a value of 2 on day 19 is in keeping with this.

My experience with upping the dose to 100 mg is that it probably will not result in an earlier ovulation, but it might. Thus, I think there is no harm, and maybe a benefit if it does accomplish earlier ovulation, so that it might not be a bad idea to increase the clomid dose to 100 mg.

As for not getting pregnant, remember that women who ovulate on their own every month do not get pregnant every month. The pregnancy rate even among the most fertile couples is probably only 25%-30% per month. Also, clomid is a great drug for improving ovulation, but sometimes has negative effects on the thickness of the endometrial lining, so ovulation does not always equal pregnancy.

The good news is that you ovulated. Although this does not guarantee pregnancy, you need to be ovulating to get pregnant. Clomid, if it is going to work, usually does so in 3-4 ovulatory cycles. I would stick with clomid, and bump up to 100 mg.
Member Comments (4)

by chinup2, Jul 08, 2007 12:00AM
I forgot to ask this. Is it necessary to using anything else with Clomid to help the 2nd round. My natural period has been irregular. It length varies from 3 months to 7 months. Thank you.

by chinup2, Jul 09, 2007 12:00AM
Thank you so much.

by sammy27, Jul 16, 2007 12:00AM
To: anybody
my question is? if a women ovulates on clomid at 50 mg.is that a good sign,and if soo. Does she necessarrily ovulate every month? cause my expierence with it ,is i ovulated with and progest was 13.well howevere i missed out.cause was told that i would not ovulate on clomid at all. but i did. Soo the next cycle started which i thought was my cycleand turned out to be brown blood with just a little blood. And it came earlier than period did andi had taking preg test at doctors office and nope not preg.SOO if  that was my period will clomid work or nope cause was told to continue it anyways still.
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