Clomid...n Metformin

hi..i have a question last month my RE had me take 50mg of clomid on days 3-7 i went back on day cycle 14 for an ultrasound and found that i had 2 good follicles..so i got enjected with a trigger shot..but i dont think i ovulated i have pcos..and i also take metformin 2000mg a day...now this month hes having me again take 50mg of clomid  days 3-7 shoudnt he had up my dose..or im ok? what are my chances to get pregnant this month? how can i know for sure that i ovulate? if clomid dosent work this month for me..what would be my next choice? Thank you in advance for the respond!
Elisa

[Forum-M.D.-SP]

Dear Elisa - I do not see any reason to up the dose. The goal of clomid is to have you ovulate, and with two follicles on ultrasound last month it sounds as if you did ovulate, particularly if you received the HCG injection (the 'trigger shot'). Also, if you had a period on your own, without needing provera or a similar medicine to bring the period on, then you had to have ovulated to get the period. As a rule of thumb with all medicines, you want to use the least effective dose since the higher the dose, the greater the risk of side effects. 50 mg seems to have done the job. If you have polycystic ovary syndrome and do not ovulate regularly, your chances of getting pregnant every month of clomid (assuming you ovulate) are probably around 20%, not that different than normally fertile women trying to conceive naturally without needing any medicines (25%-30% each month in fertile women). Hopefully you are ovulating - if so then hopefully you will be pregnant within a 2-3 cycles. Things sounded like they went well last cycle. Good luck this month!

[Jenny5]

I started taking Clomit couple of months ago. The first 2 months 50 mg and the for about 4 100 mg. I never got pregnant. Then i changet to a RE and he put me on 200 mg clomit and gave the hcg injec. I had 3 follicles but didn't got pregnant. Next cycle my doctor put on a mix of Clomit and injectable gonal F. He said that only injec. were risky for me cause i had a lot of eggs but they don't go all the way to ovulate, and the risk for hyperstimulation was big. Anyway i got pregnant the very first cycle, but miscarried at 7 weeks.
My advice is, don't try clomit especially the same dose for many times cause if it doesn't work it's not going to. And with clomit you can ovulate but very few women get pregnant. Try other options that don't take your time and money. Speak with your doctor for other options. Good luck

[taz2008]

A related discussion, does clomid n metformin work in fertility was started.