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Fertility / Infertility (Expert Forum)
worried about taking Metmorphin for infertility
Questions in the Fertility/Infertility forum are answered by doctors affiliated with USF Health. Topics covered include fertility or infertility issues, egg quality, fertility drugs and side effects, fertility tests, genetic testing, in-vitro fertilization (IVF), ovulation, relationship issues, risk factors, sperm count/quality, and surgery.
worried about taking Metmorphin for infertility
by lisa940, Nov 24, 2007 12:00AM
hi i dont no if you will be able to help me but i have got polycistic ovarian disease and endometerosis and iam trying to get pregnant i have had loads of tests and i dont no were to go from now iam taking metmorphin and i have been on clomid is there anything that will really help me to get pregnant
Doctor's Answer
by Forum-M.D.-SP, Nov 24, 2007 12:00AM
Dear Lisa940 - the chances of getting pregnant with PCO are very good. Usually the first steps are to try clomid, or a combination of clomid an metformin. The goal of the clomid and metformin is to first get you to ovulate; after all if your periods are not regular, then you are not ovulating, and you need to ovulate in order to get pregnant. Clomid succeeds in achieving ovulation probably 60%-70% of the time. You will know if clomid is making you ovulate if you are having regular periods while on clomid, and do not need a medicine like provera to bring on a period. If you are ovulating on clomid and having regular periods, then if clomid is going to work to get you pregnant it usually occurs within the first three ovulatory months on clomid, and if you are not pregnant after 4-6 ovulatory months on clomid is is wise to consider other fertility medicines. About 50% of women who are ovulating on clomid get pregnant.
If you are not ovulating on clomid, then you will know this because you will not get a period (unless of course you get pregnant), and will need provera to bring on a period. In this case, your doctor should increase your clomid dose. We usually start at 50 mg of clomid for 5 days, but go up to 200 mg a day for 5 days if required to get you to ovulate.
A good way of telling of clomid is working to make you ovulate is to have a blood test for a hormone called progesterone on day 21-25 of your cycle. Progesterone is only found in the blood after ovulation, so the presence of progesterone means you have ovulated and therefore have a chance to get pregnant. If the progesterone test is negative, then you ought to take provera to bring on a period, and try the next highest dose of clomid.
If you do not ovulate on the highest dose of clomid, or after 4-6 ovulatory months on clomid you are still not pregnant, then it is time to think of other treatments. The next step is to use injection fertility drugs, which almost always lead to ovulation. If you need to use injection drugs, it is a good idea to get a sperm count on your partner, and an x-ray of your uterus called a hysterosalpingogram to make sure your fallopian tubes are open first. You should also see an infertility subspecialist doctor, called an REI (stands for reproductive endocrinology and infertility) if clomid does not work.
As I said initially, the chances of getting pregnant with PCO are very, very high, as long as you have a focused approach to treatment.
Good luck!
If you are not ovulating on clomid, then you will know this because you will not get a period (unless of course you get pregnant), and will need provera to bring on a period. In this case, your doctor should increase your clomid dose. We usually start at 50 mg of clomid for 5 days, but go up to 200 mg a day for 5 days if required to get you to ovulate.
A good way of telling of clomid is working to make you ovulate is to have a blood test for a hormone called progesterone on day 21-25 of your cycle. Progesterone is only found in the blood after ovulation, so the presence of progesterone means you have ovulated and therefore have a chance to get pregnant. If the progesterone test is negative, then you ought to take provera to bring on a period, and try the next highest dose of clomid.
If you do not ovulate on the highest dose of clomid, or after 4-6 ovulatory months on clomid you are still not pregnant, then it is time to think of other treatments. The next step is to use injection fertility drugs, which almost always lead to ovulation. If you need to use injection drugs, it is a good idea to get a sperm count on your partner, and an x-ray of your uterus called a hysterosalpingogram to make sure your fallopian tubes are open first. You should also see an infertility subspecialist doctor, called an REI (stands for reproductive endocrinology and infertility) if clomid does not work.
As I said initially, the chances of getting pregnant with PCO are very, very high, as long as you have a focused approach to treatment.
Good luck!
