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I have had two large cysts while on clomid. The first one was gone after 3 weeks, and the second was was gone after 2 weeks. There are several different kinds of cysts, as you know. If you have not been taking any fertility drugs, yours may not be the same kind of cyst that I get. Ask your doctor what type of cyst you have and then read up on it. Especially, ask him if the cyst has fluid in it, or if it is solid. There is one type of cyst that is solid and it sometimes has to be removed, but it is rare so try not to worry. If your RE is not concerned, then you probably shouldn't be either. Hope this helps.