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Hello! i just started taking it about 3 or 4 weeks ago.. and as babybun said, i took it only once a day for 5 days or so in the evening with a meal.. i really didn' t have many side effects, maybe once or twice had stomach cramps that were pretty bad, but no big deal really, a little nausea, but defintely tolerable! got pretty hungry a few times, but thats it! I'm not insulin resistant either, and i'm actually a little underweight.. but we wanted to try any and everything we could this last cycle and so far my follies look better than ever! so i'm not sure if its coincidence or if its the metformin really working!!! GODO LUCK! : )