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possible uterine abnormality related to Recurrent pregnancy loss

by jw2121, Apr 30, 2007 12:00AM
Hello, i am 26 years old and have had 3 m/c's in the last year. I test positive for MTHFR gene mutation and positive for antiphospolipid IGg. With last pregnancy i was doing daily heparin injections and 4mg folic acid a day, thinking that was the problem, and still m/c'd at 8 weeks. My DH and i both had chromosomes checked and all are normal. Progesterone levels are normal too. My regular OB says he thinks everything will be ok next pregnancy and start ttc again. So i am 6 weks. post D&C and DH and i have been ttc for last four weeks. I just saw a specilist today for a second opinion and he said he thinks the problem may be an anatomical problem with uterus. He did an u/s and said I just ovulated a few days ago, when my DH and I also had sex. There is a very good chance i cocieved b/c i get preg. very eaisily, so now we cannot do the HSG until we find out in 2 wks if i'm preg. or not. My concern is this- if i am preg. and do have a uterine abnormality it will most likely m/c again. But if i don't m/c i would be a risk for preterm labor if i do have a uterine abnormality. Anyone have and experience with pregnancy with possible uterine abnormality? Any info. would be appreciated!
Member Comments (2)

by subaby, May 01, 2007 12:00AM
Hi there,
I was dx in October with a mullerian anomoly (uterine abnormality). I had several m/c's and went to see a RE. First thing he did was order a saline ultrsound which confirmed that I had a septated uterus. Basically, there is a band of tissue that comes down from the top of my uterus. He speculates that my embryos were attaching to the septum (which is avascular--doesn't have good blood flow) and then they would m/c due to lack of nourishment. I had a very, very simple surgery to fix this problem and now we are ttc. If you have a septum in your uterus, you chance of m/c can be 80-90%. However, after the surgery, your chances of m/c drop to the level of a normal person. I don't know if you have this or not, but just wanted to let you know my experience. It is a treatable condition. I encourage you to not drive yourself crazy until you know something (I know that is so much easier to say than do)! However, if you do find out you have a "wacky" uterus, there is a great group on Yahoo with women just like us with tons of wonderful support and success stories.

I wish you all the best. I know how scary and frustrating this can be. I am so glad that you have taken the steps to go to a specialist. They will figure out whats going on. I'll be thinking about you and I will say a prayer.

by lil_otis, May 01, 2007 12:00AM
I have had several miscarriages (I also get pg very easy) and I don't know what an HSG is but the doctor injected dye in to my uterus and did an x-ray. He was checking for the septum thing, which he was pretty sure I didn't have because I have 2 kids already, anyway I didn't have the septum and the test really didn't tell me a whole lot. I am very frustrated because I know I can conceive and have babies because I have two. My husband and I both feel we should have one more but I keep having all these unexplained miscarriages. Anyway, I hope you have better luck. Just know that the HSG may not tell you as much as you want it to.
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