Preliminary studies suggest improvements in symptoms of fibromyalgia with vitamin D supplementation. Recently, a randomized controlled study found that increasing vitamin D blood levels from a mean of 19 ng/mL to about 50 ng/mL was associated with a modest decrease in fibromyalgia pain (a 20 point decrease on a 100 point scale). The study involved 30 adults (mostly women) in Austria with fibromyalgia. Most of the participants started the study with vitamin D levels below 24 ng/mL and were given 2,400 IU of vitamin D3 daily, while those starting with levels between 24 ng/mL and 32 ng/mL were given 1,200 IU daily. Treatment continued for 20 weeks or until vitamin D levels reached 48 ng/mL (levels in several patients went as high as 55 to 93 ng/mL). Twenty-four weeks after supplementation ended, pain returned to the original level in the group. (science Direct)