Hi....I was on predisone about two years ago to control my pain along with inflamation (inflammation) becuz of very high sed rate......It made me again alot o weight...it did help with my pain along with mobic,cymbalta, and tramdol....whew!!! I was on 30 mil gram twice aday ....then it went down 25,20,15,10 and so on until i was at 3 once a day...it didnt change my life overnite but it helped out about 40% with my pain and stiffness.....It was about eight months i was on it. I hope this helps you out....I think that you have to weigh your options and dont stay on it long..It has side effects.....take care
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