the 2nd metatarsal base area bears a lot of weight when the foot hits the ground. we call it the "key stone" of the foot.
if there was a fracture at the base (intra-articular), then you could have arthritis in the area. i typically have the patient wear a surgical boot for 6 weeks and then transition to a stiff sole shoe (surgical shoe). if the patient continues to have pain when in a shoe and orthotics after 3 mos from date of injury, i fuse the joint (the base of the 2nd metatarsal to the cuneiform). patients typically do well from then on.