For several years Mayo has been treating me for GERD (severe). 16 months ago, I experieneced what I thought was a heart attack and took myself too the ER where they kept me overnight. This has happened 3 times. Mayo has done a complete batter of testts on me including ultra sounds of the bladder, colonoscopy, lliver, gallbladder, ovaries, etc. I was burning from the time I woke in the morning until I got up and then it stopped. They suggested 2 Nexium a day which has helped with the burning. I now experience buring of the shins, burning of the vaginia and rectum and they are still calling it GERD. I take Tyelenol or Darvocet N100 and it helps but doesn't eliminate the pain in the rectum. I hve normal BMs followed sometimes by mucosy ones and thin ones. I also experience low back pain with these symptoms. This problem wakes me during the night. It seems that it can't possibly be GERD but what do I know? Thank you for your help.