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GERD (Acid Reflux)  (Expert Forum)
 | 
Reaction to PPI
Answered by
Ratnakar Kini, MD - Gastroenterology, Pediatrics, acid reflux, gerd, colitis
Gastroenterologist & Hepatologist India
This forum is for questions and support regarding Gastroesophageal Reflux Disease (GERD) / Acid Reflux with topics including: Causes, Constipation, Diagnosis, Diarrhea, Drugs and OTC medications, Living with GERD, Loss of Appetite, Preventing Flare-ups, Research, Risk Factors, Symptoms, Support, Surgery, Tests, Treatments.

Reaction to PPI

by Gloomy_Observer, Dec 12, 2008 08:53PM
Hi

Please, please can someone help me!

I have had GERD for years. At first, I took Prilosec 40 mg as things were very difficult for me acid-wise, then slowly reduced to 20 mg. After a while my doctor change me to Nexium 20 mg. That was fine for years too. Then I shifted back to prilosec to save money. Again, no problem at all. Very happy story...

...then, a few months back I started to worry about how long I had been on prilosec for (9 years on PPI total), so I tried to reduce the dosage to 10 mg (one tablet every 2 days). For 6 weeks all was fine - and the GERD game back with a bang!

Anyway, I started taking Prilosec 20 mg a day again, but went to the doctor anyway. He said the acid was VERY strong again and put me on Nexium 40 mg for a week. Things started to improve rapidly, as I knew they should.

When the Nexium ran out I went back to taking Prilosec again (it is 10x cheaper here and I had been fine with it). As the acid was VERY bad, I was on 60 mg a day for 2 days, then reduced back to 40 mg.

Well, the acid is slowly going. BUT since I switched back to Prilosec I have a wierd, dizzy, spaced-out feeling ALL the time; like I am watching life on TV, and slightly blurred vision at times.

It seems I have developed a reaction to Prilosec!! But how can this be? I was fine on it for years and years and years!! Can someone tell me if it is possible to suddenly react badly to a previously very-well tolerated medicine like this?

Now I am terrified about my options. I can't live like this (it's driving me crazy!); I am thinking of going back on Nexium for a week and seeing if my brain 'de-fogs' in that time. If it was the Prilosec causing it, should I see an improvement in 7 days?

And if Nexium doesn't improve how I feel, then I am stumped...

PLEASE, please if anyone has experience in this area, let me know!!


Thanks so much!!!

  

by Ratnakar Kini, MD, Dec 14, 2008 05:29AM
Hi,
Dizziness and blurred vision can occur with Prilosec.
These are rare and transient reactions which subside on stopping the medication.
Consult your doctor if they persist.
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The information provided is for patients’ education only and is not a medical advice. Always consult your personal physician for complete evaluation of your health problem.

- Ratnakar Kini M.D.
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