GASTROENTEROLOGY / DIGESTIVE DISORDERS EXPERT FORUM
Advise regarding CHB status.

Advise regarding CHB status.


  
  Dear Doctor
  In 1993, I had a routine Hepatitis B screening wherein it was discovered
  that I had acquired HBsAg NEGATIVE & ANTI HBs POSITIVE(greater than
  120mIU/ml) status. Based on the above, it was told me that I had
  suffered a subclinical infection which had me naturally immunized and
  that I was NOT a carrier of the disease; healthy or otherwise.
  Recently, I was required to carry out some blood investigations, among
  which included Hepatitis B screening. However, only the ANTI HBe(EIA
  method) was done and that returned POSITIVE. No other said viral
  parameters were done. Liver enyzmes, AST(21U/L) & ALT(38U/L) were normal
  except for GGTP which was high at 154U/L. For the non-fasting lipids;
  LDL was at 140MG/DL(high) and CHOL/HDL RATIO was at 6.2(high).
  Please advise me:
          IF further investigations are required for CHB.
   The persistence of ANTI HBe for these many years, which to my understanding is present
   during the convalescence phase of active Hepatitis B.
          Any correlations between the elevated GGTP and CHB.
          If but any correlations between the elevatad levels of GGTP & LDL.
          
   The need to consult a local Hepatologist.
  The above investigations were carried at different centers by different
  requesting physicians.
  Thank you for your generosity and expertise.
  Hoping to hear from you.
  Sincerely,
  Manny
___________
Dear Manny,
The anti HbS and the anti Hbe indicate that you had hepatitis b infection and have developed an immune response.  The cause for youe wlwvated GGT is not evident.  An ultrasound is necessary to evaluate the bile ducts and the liver.  Statistically, the most probable cause is fatty liver but other conditions must be considered.  This initial step of ultrasound can be arranged by your primary physician.  He can then determine if you need to see a hepatologist.
This information is presented for educational purposes.  Always consult your primary physician fro specific medical questions.
HFHSM.D.-rf
*keywords: hepatitis B
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