Attenuated FAP

Subject: Attenuated FAP

Forum: The Gastroenterology and Liver Diseases Forum

Hello,
I am a 38 y/o female, I have an APC gene mutation in segment 4. The diagnosis was Attenuated Gardner's uuSyndrome. I have one skull osteoma.
Colonoscopy: 2 small adenomatous polyps removed from right colon
EGD: Small area of stomach polyps, Duodenum was clear
Abdomen & pelvic CT: Normal
My father 65 has had multiple abdominal surgeries for this syndrome. Presently he has metastic liver cancer from his colon. Paternal grandfather 88 has visible skull osteomas and palpable abdominal masses. Brother 40 has jaw osteoma and 4 polyps (1 adenoma) removed.
For unrelated orthopedic conditions I have been on Daypro 1200mg 6/95-7/98, Sulindac 400mg 8/98 (stopped, ulcer), Arthrotec 150mg 10/98-1/99 (stopped, ulcer), Celebrex 200mg 2/99 to present. I am wondering if my use of NSAID's could have slowed down the FAP progression? I know there have been a past study on Sulindac and an unpublished recent study of Celebrex, but I am unaware of any on Daypro or Arthrotec.
My GI doctor recommends retesting in 2 years, does this sound correct? I'm asking because my father's cancer was very aggressive, originated in his cecum and developed  to 4th stage
over a 14 month period between colonoscopies.
I'm so pleased that this forum is available to us!
Thank you, Tonya
  










Follow Ups:


Re: Attenuated FAP HFHSM.D.-ym 4/26/1999
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Attenuated FAP Tonya 4/26/1999
(1)

Re: Attenuated FAP HFHSM.D.-ym 4/27/1999
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