Can you have an allergy to amylase?

For the past several years I have been suffering from an unknown digestive issue.  Symptoms include diarrhea, cramping, distended abdomin (abdomen), bloating, gas, and excessive burping leading to nausea.  My GP tested me for H Pylori, among other things, as well as for gluten allergy.  All came back normal so he sent me to a gastroenterologist.  Had an upper GI, everything was normal.  The gastroenterologist was baffled at my symptoms that didn't really seem to have a pattern, like when I eat certain foods.  So she stuck me on Aciphex for six months and that was it.  The Aciphex didn't really seem to help much.  

I recently have been going to a chiropractor for an unusual bend in my neck, and hoping that getting my lower back aligned might help my digestive problems.  He told me that they could order an allergy test that would test for allergies to foods, metals, etc.  So I had my finger pricked for blood and gave a saliva sample.  The test "results" indicated that I had a significant allergy to amylase.  On a scale of 1 to 100, mine registered at 73.  So if I had a drop of blood with 100 red blood cells, 73 would be damaged.  He told me to avoid milk and ice cream, but other foods made from milk were ok, so long as the milk was boiled (cheese, yogurt, etc.).  Now I realize this is coming from a chiropractor....But can you be allergic to amylase?  Was I given the correct advice?  Do you have any further advice?

Thank you in advance.

[Kevin Pho, MD]

I am not an allergist, so my answer is going to be limited.

It is possible to be allergic to amylase, leading to symptoms consistent with malabsorption.  Further testing with an allergist can be done to exclude this possibility.

I would also pursue more GI testing to complete the workup.  I agree with the upper endoscopy.  I would also consider imaging with a CT scan as well as more specialized tests like a 24-hr pH study or an esophageal motility study.  

Breath tests can also be done to exclude lactose intolerance or evaluate for bacterial overgrowth.  

These options can be discussed with your personal physician.

This answer is not intended as and does not substitute for medical advice - the information presented is for patient education only. Please see your personal physician for further evaluation of your individual case.

Kevin, M.D.
www.kevinmd.com