Elevated Levels from Blood Chemistry Results - Why? How?

43 y.o. Fe, 5'8" 152 lbs - workout 3 - 4 times per week. BP 106/70 Pulse=60 I have a clean diet heavy with fresh fruits & vegetables, chicken & fish...no red meat or pork. I have been treated for depression since July of 2006 first w/ Lexapro & Xanax and changed to Wellbutrin 150mg per day & Xanax 0.5mg in January 2007. I am also a heavy coffee drinker; occasional glass of wine 3 or 4 times per month. Needless to say I was shocked to receive the following results from my insurance provider:

Glucose 140
Fructosamine 1.8
HGB A1C 5.8; BUN 13
Creatinine 0.8
Alkaline Phos 71
Bilirubin 0.4
AST 91; ALT 89; GGT 89
Total Protein 6.7
Albumin 4.1; Globulin 2.6
Cholesterol 224
HDL 50; LDL 97
Cholesterol/HDL 4.5; LDL/HDL 1.96
Triglycerides 381; Creatinine 115.7
Hemoglobin NEG
DIU NEG; BAB NEG
Protein/Creatinine Ration 0.10

I am totally lost as to what could cause these elevated levels.

[Kevin Pho, MD]

The lab tests are significant for elevated liver function tests, triglycerides and sugar (if the test was done fasting).  

The liver tests should be further evaluated, as there are many diseases that can lead to this finding.  An ultrasound, as well as further blood tests to look for hepatitis should be done.  I would abstain from alcohol and repeat the tests serially.

As for the elevated triglycerides, there is a genetic component this this as well.  So, even if the diet is appropriate, you can still have high triglycerides.  A referral to a dietician can be considered to evaluate dietary options.  If the levels continue to be elevated, there are medications to target the triglycerides.  

These options can be discussed with your personal physician.

Followup with your personal physician is essential.

This answer is not intended as and does not substitute for medical advice - the information presented is for patient education only. Please see your personal physician for further evaluation of your individual case.

Kevin, M.D.
kevinmd_