GERD & Motility disorder

  : I am 30 years old and have had GERD for 3 years now.  I currently take 150 mg. of zantac at
  : bedtime, 30mg. of prevacid 2x daily and 20mg. of propulsid
  : 2x daily.  I still continue to have GERD, increased burping
  : acid coming back into mouth), food sticking in throat
  : and nausea with heartburn.  I had a endoscopy done which showed
  : severe esophageal redness and some polyps in the duct into my
  : gallbladder.  My doctor has said that my GERD is caused by a
  : esophageal motility disorder, which he said could be congenital.
  : I have also had esophageal spasms, that were very painful.  
  : I can feel the heartburn through to my back.  I have adjusted my
  : diet in the past to no effect, so the doctor feels that eating
  : has nothing to do with it.  I get heartburn from drinking water
  : or eating oatmeal. I also have what is called "lazy colon" and
  : suffer from daily intestinal gas and chronic constipation.
  : My doctor has said he may want to do some more tests to study
  : the motility of my esophagus.  I have read a lot of information
  : about the nissen fundoplication and wonder whether that
  : can correct a motility disorder? Or, will I have to take
  : medication for the rest of my life and still suffer.  
  : Could I become immune to the medication because I have been
  : taking so much for so long? I would almost be willing to go
  : through with the surgery if it would make me feel better.
  Hi!
  Just curious....How long have you been taking Propulsid?  I had a stomach dysmotility disorder (at least, that's what my gastroenterologist decided by process of elimination).  The Propulsid helped but I stopped taking it when I developed premature ventricular contractions.  I'm wondering whether Propulsid alters electrolyte balances, particularly in regard to magnesium.  I have been taking a chelated form of magnesium supplements which helps the PVC's somewhat and I haven't had any stomach problems!  I think the magnesium helps with stomach contractions as well.  
  Would the doctors on this forum please comment on Propulsid and electrolyte imbalances?
  Thank you,
  Mary
  

[HFHSM.D.-rf]

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Dear Mary,
Propulsid does not cause electrolyte abnormalities.  Patients with electrolyte abnormalities who take Propulsid have an increased risk of cardiac rhythm problems.
This information is presented for educational purposes.  ASk specific questions to your personal physician.
HFHSM.D.-rf
*keywords: Propulsid
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