GASTROENTEROLOGY / DIGESTIVE DISORDERS EXPERT FORUM
Liver and the thryroid

Liver and the thryroid

what effect can hypothroidism have on the liver? a recent blood test indicated that two of the tests for liver enzymes were slightly elevated, since my thyroid tests were slightly low I am wondering if this may be a connection
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The GI manifestations of hypothyroidism are the following:
* Constipation
* Decreased taste sensation.
* A modest weight gain due to decreased metabolic rate and accumulation of fluid (nonpitting edema) that is rich in glycosaminoglycans is a frequent finding. However, marked obesity is not characteristic of hypothyroidism.
* Ascites is a rare finding.

I am not aware of direct liver damage from hypothyroidism.  However, several studies have shown that hypothyroidism can elevate the liver enzymes themselves without clear liver damage - the cause an reasons for this are unclear.  

Followup with your personal physician is essential.

This answer is not intended as and does not substitute for medical advice - the information presented is for patient education only. Please see your personal physician for further evaluation of your individual case.

Thanks,
Kevin, M.D.

Bibliography:
Pratt.  Approach to the patient with abnormal liver function tests.  UptoDate, 2004.
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