Possible HBV infection?

In 1991, my wife had HbsAg negative before coming in this country. We were 35 then. Before 1991, both of us had several HbsAg negative tests. Forgot anti-HBs result.

In 1990-91, I had a roommate who had liver problem (don

[Kevin Pho, MD]

To answer your questions:
1) Typically, the anti-HBc is present after exposure or resolution of acute infection.  Studies suggest a low rate of infection with the presence of this antibody (0.4 percent in blood donor series).

2) 3-4 months would be sufficient time for antibodies to show up during bloodwork.

3) That is correct.  However, the presence of anti-HBc is not normal during a vaccine.  This is normally from an acute infection, and increases the transmission risk.

I would discuss these questions with your personal physician.

Followup with your personal physician is essential.

This answer is not intended as and does not substitute for medical advice - the information presented is for patient education only. Please see your personal physician for further evaluation of your individual case.

Kevin, M.D.
kevinmd_