Primary Sclerosing Cholangitis

I am a 55 yr old female with a history of gastritis going back to age 25; gall bladder removed in 1989, four ERCP's in NYC; dr suspects PSC; frquent gallstone like attacks in recent months; having MRCP, upper GI this wk; common bile duct very narrow and has branches (genetic fault?). Currently in pain (back upper right, below right wing), and fatigued always.  No Hep B or C, non-alcoholic; methadone 40mg since 1975.  Since long history and 4 ERCPs, last one 1999 in Beth Israel North, Jerome Siegel, Dieterich in charge.  What can my husband expect if diagnosis correct.  Very vague, I know, but input by board or thread may be helpful to husband.

[Kevin Pho, MD]

PSC is related to a variety of complications if not untreated.  This can include cholestasis, stricture formation, cholelithiasis, cholangitis, cancer of the bile ducts as well as colon cancer.  Liver failure as well as portal hypertension also can be present if the disease is untreated.

Medical therapy, such as UDCA as well as endoscopic therapy like stenting can all be considered.

These options can be discussed with your personal physician.

Followup with your personal physician is essential.

This answer is not intended as and does not substitute for medical advice - the information presented is for patient education only. Please see your personal physician for further evaluation of your individual case.

Kevin, M.D.
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