GASTROENTEROLOGY / DIGESTIVE DISORDERS EXPERT FORUM
Recurring Canker Sores and Crohn's disease

Recurring Canker Sores and Crohn's disease

An update to the previous post:
For the past 3 years, I have been getting recurrent canker sores. They would apprear twice a month. They disappeared only when I was in my secong and third trimester of pregnancy. I did various tests and a colonoscopy to rule out Crohn's disease. I also did the ASCA and ANCA blood tests. My colonsocopy was normal. ANCA was negative but ASCA was positive. I dont have the classic symptoms of Crohn's (diarrhea).
is a positive ASCA an indicator of Crohn's? My GI doctor said that my case is sub- clinical - like I almost dont have it. I was also recently diagnosed with reflux through an endoscopy. I also was positive for H. Pylori. I am not sure if its' related

Looking for your opinion! Thanks.
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This question is similar to your previous one, and I'm not sure I have anything new to add.

Yes, ASCA positive can be indicative of Crohn's.  Further tests can be done with the anti-OmpC antibody test.  

Imaging can include a small bowel series, or more invasively, a push enteroscopy.

If the tests are negative, then either the Crohn's is subclinical, or there is another disease that is causing your symptoms.

I am not aware of H Pylori or reflux being associated with canker sores.

These options can be discussed with your personal physician.

This answer is not intended as and does not substitute for medical advice - the information presented is for patient education only. Please see your personal physician for further evaluation of your individual case.

Kevin Pho, M.D.

KevinMD.com
Twitter.com/kevinmd
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