elevated GGT

I am a very healthy 61 year old male.   I do however have high cholesterol which is controlled at present by 40 mm of lipator. I cannot take mevacor or zocor because of elevated liver enzymes. I have an annual test for cholesterol and liver issues and prostate etc.  My personal physician always indicates to me that my enzymes are high but acceptable.  I do not know the number.   I recently applied for additional life insurance, all my test scores were terrific except for the GGT level and that came back at 69.   I drink about 4-5 glasses of red wine per week.  Should I stop the alcohol altogether?  Would it be prudent to experiment with a lower dose of lipator?  Or did the test occur on a bad day?  Would you suggest a re-test? Or can I just live with the 69 reading as a lessor of all the other evils? As a 61 year old marathon runner and biker, 5-10 163 lbs with untreated cholestrol at 320, LDL at 220 and HDL at 65 I would asssume I would be asking for big problems if I stopped the lipator.  Or to be a realist does the liver get me or does heart disease?   Thanks for your time.  LFP

[Kevin Pho, MD]

I would repeat the liver tests after abstaining from alcohol.  If the rest of liver enzymes were normal, it is less likely that the lipitor is the culprit.  If the GGT remains elevated, I would consider an abdominal ultrasound to evaluate the liver and gallbladder.  

If the remaining tests are negative, then more intensive periodic monitoring (i.e. every 3-6 months) may be necessary to ensure the liver tests do not trend up.  

Followup with your personal physician is essential.

This answer is not intended as and does not substitute for medical advice - the information presented is for patient education only. Please see your personal physician for further evaluation of your individual case.

Kevin, M.D.
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