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Gastroenterology (Expert Forum)
Barrett's Esophagus and Accutane
This forum is for questions regarding Gastroenterology issues such as Acid Reflux (GERD), Barretts Esophagus, Colitis, Colon/Bowel Disorders, Crohn's Disease, Diverticulitis/Diverticulosis, Digestive Disorders, IBS, Stomach Pain.
Barrett's Esophagus and Accutane
by Arty__0__0, Jul 06, 1998 12:00AM
My 15 year old son was diagnosed with Barrett's recently. He is taking Prilosec 20mg 2 times a day. Also has an acne problem that his dermatologist wants to treat with Accutane since all otther meds and treatments have failed. Neither Gastro or dermatologist will advise if any problems in taking accutane with his condition. A PH Probe test was recently completed with results showing Prilosec controlling tha acid for 23 outt of 24 hrs. Any problems with the Accutane. Should we watch for any specific symptoms. All info will be appreciated.
Thank You
Arty
____________
Dear Arty:
Accutane (isotretinoin) remains the most effective anti-acne therapy available. Since it was approved for the treatment of severe acne in the early 1980s, more that 7 million patients have received this medication..
The most common side effects of Accutane are dryness of the mouth, nose and eyes. It also commonly produces some redness of the facial skin with increased sensitivity to ultraviolet light. About 15% of the patients taking Accutane complain of some muscle or joint pain, usually relieved with over-the-counter analgesics like Tylenol.
Because in some rare cases patients taking Accutane developed abnormal liver blood tests and high cholesterol, most physicians routinely check these blood tests before starting treatment.
Accutane has also been safely used in many chronic diseases such as inflammatory bowel disease (ulcerative colitis and Crohn's disease), epilepsy, diabetes, multiple sclerosis, renal insufficiency and heart or kidney transplant patients.
Using a computerized medical literature database we could not find any references to Accutane treatment in Barrett's Disease or interactions between Accutane and Prilosec. One source of information on adverse events occurring during treatment with Accutane is the Roche Safety Database. They did not have any reported interactions between Prilosec and Accutane or in patients with Barrett's esophagus.
Despite the lack of specific information about the use of Accutane in patients with Barrett's esophagus taking Prilosec, it is probably safe to remain under the supervision of your Dermatologist.
This information is provided for educational purposes only. Always consult your physician for specific medical questions.
HFHSM.D.-ab
*keywords: Barrett's esophagus, Prilosec, adolescent, Accutane
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