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Stomachprob, it's possible that the C. diff may not respond at all to the flagyl at this point in time, but your best bet is going to be working with an infectious disease specialist. Push to get that referral and get it as soon as possible. In the meantime, check out the cdiffsupport.org website. There are a lot of people there who have dealt with what you're currently going through and they may be able to offer a lot of good advice.