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Gastroenterology  (Expert Forum)
 | 
Deciphering colonoscopy/other results for IBD or misc
Answered by
Kevin Pho, MD - Internal Medicine
KevinMD.com
This forum is for questions regarding Gastroenterology issues such as Acid Reflux (GERD), Barretts Esophagus, Colitis, Colon/Bowel Disorders, Crohn's Disease, Diverticulitis/Diverticulosis, Digestive Disorders, IBS, Stomach Pain.

Deciphering colonoscopy/other results for IBD or misc

by theguythere, Jul 23, 2007 12:00AM
I'm mid-twenties of normal weight w/ lifelong cylic IBS symptoms - severe diarrhea for years when younger, then constipation w/ diet changes.

Things I know:
It's hereditary; never bloody stools, often mucus; blood all normal; Abd Ultrasound normal; No other major medical incidents; unrelated head CT scan normal.

Things I notice:
Feelings of lethargy; lack of tooth enamel, even w/ F- treatments and regular care; Occ joint/foot-leg numbness/pain

Visually, colon normal, mild gastritis in antrum. Biopsies:
Duodenum & Terminal Ileum: Mucosa W/o Significant Changes
Antrum: Mild Chronic Gastritis, Inactive, W/o Intestinal Metaplasia. H-Pylori Not Seen.
Right Colon: Mucosa Showing Mild, Nonspecific Chronic Inflammation w/ Lymphoid Follicle
Sigmoid Colon: Mucosa W/o Significant Changes.
Rectum: Mild Chronic Proctitis, W/o Architectural Disarray.

Is the chronic inflmm indicative of IBD, even w/o bloody stools, clinical anemia, or ulcers? lymphocytic or another micro-colitis? Chrons & UC ruled out?

Where is more info about non-Chron/UC IBD? What are good sources of technical info for diagnosis of related diseases, like literature clinicians or researchers follow?

Are there DNA tests that are specific positive indicators rather than just tell me what I already know?

I have noticeable, painful reactions to fructose, but been rebuffed by PCPs regarding fructose test. Is it worth doing these tests if they're just symptoms of a form of IBD?

General ideas?

by Kevin Pho, MD, Jul 23, 2007 12:00AM
You have had a comprehensive workup thus far.  

The biopsies would rule out many of the major disorders that can lead to these conditions.  The proctitis and inflammation may be associated with ulcerative colitis - although this is not definitive.  Typically, a source like Harrison's Internal Medicine (found a medical libraries or bookstores) is used for more physician-specific information.

I am not aware of DNA tests being routinely used for the diagnosis of UC.  

Fructose intolerance can be considered - although this is uncommon.  The appropriate breath tests can be done if this is suspected.  

If the symptoms continue, I would also send the stools off for fat malabsorption as well as obtaining blood tests for celiac disease.

Followup with your personal physician is essential.

This answer is not intended as and does not substitute for medical advice - the information presented is for patient education only. Please see your personal physician for further evaluation of your individual case.

Kevin, M.D.
kevinmd_
Member Comments (1)

by lizziecee, Jul 23, 2007 12:00AM
To: theguythere
Free technical information on UIBD is available from the National Assocn. for Colitis and Crohn's: website is: www.nacc.org.uk
This an English charity support/research  organisation for those with IBD.
You could also try looking at the CCFA site:  Crohn's and Colitis Foundation of America. I haven't got their URL, but you could try googling it.
Good luck.
liz.
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