EGD results

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  I recently had an EGD performed to rule out celiac
  as a potential cause of Zn and Fe malabsorption.
  Biopsy results showed slightly shortened villi in
  some areas, but the findings were not consistent
  with celiac sprue. Biopsy results did show marked
  chronic inflammation within the lamina propria
  consistent with chronic duodenitis. No organisms
  were identified.
  What causes chronic duodenitis? Is this inflammation
  driven by stress? Food allergy? Bacteria?
  Also, given the associated malabsorption problem,
  what can be done to reduce the inflammation? Does
  chronic duodenitis have long term implications?
  Many thanks,
  Chris Lund
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Dear Chris,
Chronic duodenitis is a nonspecific term.  Often duodenal inflammation is due to acid-induced damage.  These changes, however, should not cause malabsorption.
Blunted villi can be seen in conditions of bacterial overgrowth as well as partially treated gluten sensitive enteropathy.  Fonally, there is a condition called tropical sprue that has the same histological features but is the result of infection.
Additional investigations are necessary to better define the mechanism of your malabsorption.
This information is presented for educational purposes only.  always ask specific questions to your personal physician.
If you wish a second opinion, we would be happy to see you in the Division of Gastroenterology at henry ford Hospital. To arrange an appoinment with Dr. Fogel, one of our experts in the treatment of intestinal disease, you should call our Physician Referral Line at [phone]
HFHSM.D.-rf
*keywords: malabsoprtion, duodenitis
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