Member Comments are provided by individuals and reflect their personal opinions only. Under NO circumstances should you act on any advice or opinion posted in this forum.  ALWAYS check with your personal physician before taking any action regarding your health! MedHelp International and our partners, sponsors and affiliates have no obligation to monitor any comments posted on this site, or the content and/or accuracy of such exchanges. MedHelp International does not endorse the views of any user.
Gastroenterology  (Expert Forum)
 | 
Enlarged Spleen (22cm) with cysts and lesions
Answered by
Kevin Pho, MD - Internal Medicine
KevinMD.com
This forum is for questions regarding Gastroenterology issues such as Acid Reflux (GERD), Barretts Esophagus, Colitis, Colon/Bowel Disorders, Crohn's Disease, Diverticulitis/Diverticulosis, Digestive Disorders, IBS, Stomach Pain.

Enlarged Spleen (22cm) with cysts and lesions

by stacyj, Jun 02, 2005 12:00AM
I am 35, female 115 lbs. I have an enlarged spleen with cysts and lesions. It is also rough as opposed to being smooth. My plateletts are just below normal (128). I have had many tests (CT scans and ultrasounds) that show the enlarged spleen. Everything else is pretty normal. I have the Leiden Factor V blood disorder. I had a HIDA scan that showed my gall bladder worked at 2 percent. My doctor mentioned that it's possible that I could have a primary splenic lymphoma. I am waiting for my bone marrow biopsy results. What are the chances of having a lymphoma that is contained within my spleen? Wouldn't a CBC show something? What would be the procedure for curing the lymphoma if that is the case?
Thank you,
Stacyj

by Kevin Pho, MD, Jun 04, 2005 12:00AM
To answer your questions:
1) Without examination, I cannot give an estimate of what the chances are that lymphoma is causing the spleen to be enlarged.  However, with the imaging tests you have had done (i.e. CT scans and ultrasounds), this possibility may be less likely.  

2) Yes, the CBC (as well as the peripheral smear) is important in the diagnosis of an enlarged spleen.  However, there are some diseases that can present with a normal CBC.  

3) If it is indeed lymphoma, treatment would depend on the size of the cancer as well as whether it has spread.  Without knowing that, it is tough to speculate on the method of treatment.  

Followup with your personal physician is essential.

This answer is not intended as and does not substitute for medical advice - the information presented is for patient education only. Please see your personal physician for further evaluation of your individual case.

Kevin, M.D.
Medical Weblog:
kevinmd_b
Member Comments (2)

by surgeon, Jun 04, 2005 12:00AM
CBC wouldn't necessarily show anything. Treatment would be splenectomy, with or without chemotherapy depending on the final details.

by nst0199, Jun 21, 2005 12:00AM
Enlarged Spleen can mean portal Hypertension.  This will enlarge your spleen and will also make your spleen burn up platelets like crazy.  Normal platelets is 140-400.  With out knowing your Past medical history and your normal blood pressure history.  If you have any questions its best to talk with a well known Liver Specialist.

by shoky, Oct 04, 2009 08:40AM
A related discussion, I have an Overian cyst with enlarged spleen was started.
Continue discussion
RSS Expert Activity
Sad cases of Animal Cruelty
15 hrs ago by Thomas Dock, Vet. Technician
Cost and Availablity of Medical Car...
23 hrs ago by John C Hagan III, MD, FACS
Behavior Medications for our Pets -... 
Dec 17 by Jim Humphries, B.S., D.V.M.