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Gastroenterology  (Expert Forum)
 | 
Familial hyperalphalipoproteinemia
This forum is for questions regarding Gastroenterology issues such as Acid Reflux (GERD), Barretts Esophagus, Colitis, Colon/Bowel Disorders, Crohn's Disease, Diverticulitis/Diverticulosis, Digestive Disorders, IBS, Stomach Pain.

Familial hyperalphalipoproteinemia

by Vicki__0__0, Oct 17, 1998 12:00AM

  I am trying to find out info on
  familial hyperalphalipoproteinemia & am not having any luck.
  This seems to be a very rare genetic condition that no one
  seems to know much about.
  My Lipid panel: total cholesterol: 176 (128-200); triglycerides:
  99 (<200); HDL: 106 H (35-86); LDL: 50 (0-130); VLDL: 19
  (no ref); LDL/HDL ratio: 0.5 (0.0-3.0); CHOL/HDL ratio: 1.7
  Increased apo A-I only leads to Familial hyperalphalipoproteinemia,
  pregnancy, or weight reduction. I am 42, had a hysterectomy 14
  yrs ago, & have been on estrogen since that time. I am 120 lbs
  & have been all of my adult life. My mother died 5 yrs ago
  with cirrhosis of the liver, unknown cause. She did not drink
  or have hepatitis. An autopsy was done but gave no answers.
  Increased HDL levels lead to liver disease according to what I
  have found so far which is one sentence in a lab book. I am
  hoping that you can shed some light on this rare condition or
  direct me to where I can find some more info. I am
  trying to obtain my mother's lab work but don't think she ever
  had a lipid panel done so probably won't do me any good. In 2 mos
  I am having another panel done to make sure the first one wasn't
  a fluke. However, it is awfully coincidental that my mom died of
  liver disease. There don't seem to be any symptoms until your
  liver starts to wear out & you actually develop liver disease.
  Is there any treatment to lower the HDL? Is steroids or liver
  transplant the only answer?
_____________
Dear Vicki,
A Medline literature earch did not identify articles that would allow me to answer your questions.  I suggest that you find an endocrinologist to help you with your questions.
HFHSM.D.-rf




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