I have had acid reflux for about 7 years. It started out mild, then over the years got very bad. I take Omprazole (prilosec) morning and night, sometimes Rantidine (commercially known as Zantac) for really bad days. I can't eat much at a time (small stomach and easily upset by large meal) so I eat about 12 times a day (small amounts) to keep it stable. I even keep granola bars/snacks with me everywhere I go because in a matter of not eating for a couple hours the acid can start to build up and get very bad.
I've seen stomach doctors, had endoscopes, etc. It seems to run in my family. My grandfather had it bad, and my 2 brothers do too. One brother actually was foolish enough to ignore it and put up with the pain that he developed ulcers, which have mostly healed now that he is taking Omeprazole and such. My Intestines also get worked up in a knot with pain at times. I've woken up in the middle of the night after forgetting to eat before sleep with HORRIBLE acid pain. I'll drink down a glass of water/alka-seltzer and sometimes throw up everything because it hurts so bad. I can even taste how acidic the vomit is. Like it could dissolve metal.
Over the last few years my back has started to bother me. I ignored it as long as I could and finally started taking 20mg of Oxycodone (not percoset with Tylenol/acetaminophen because I don't like Tylenol or putting stress on my liver - so I take ibuprofen/aspirin instead.) I really don't like how they mix so much Tylenol with pain meds, I enjoy wine and while I don't think I'm drinking to the point I'm doing liver damage, I don't want to be taking Tylenol. Luckily my doctor was fun with just prescribing the pure Oxycodone after I told him I did not want extra meds for my liver to work on.
I can tell you this. The Oxycodone is *as much if not more* a relief to my stomach/digestive track as it is to my back. I don't know why, but it very quickly seems to greatly reduce acid production. If I didn't have back problems, I would still take the Oxycodone for my stomach alone. Although not many doctors would prescribe it for just that I think. For 4+ years I've been in nearly constant discomfort and pain with my stomach and sometimes esophagus (when I've let it go too far), and for the last 4 months of being on low dose of Oxycodone, I've had almost nothing. I even have lowered my dose of Omeprazole (Prilosec) to 1 pill a day or 1 pill every 2 days and my stomach stays feeling SO much better.
I have read Oxycodone can upset some people's stomachs. It doesn't mine, I take several other meds for other conditions and they never really seem to upset my stomach, just acid production does.
My dose is 20mg morning, 20mg 5hrs later, then 10mg evening as I kind of have a hard time sleeping on it. It makes some people sleepy, with my it activates my mind increasing my long existing condition of insomnia.
I'm glad someone else is questioning this. My Doctor was surprised the Oxycodone has a positive side effect on my stomach.
If anyone else has had the same benefit with Oxycodone relieving stomach acid production please post. I can't think we are the only ones.
Someone also mentioned it in this thread
http://www.medhelp.org/posts/GERD-Acid-Reflux/Oxycodone-stopping-burning-stomach/show/1281602