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Gastroenterology (Expert Forum)
Liver biopsy cant get straight answer
Answered by
Kevin Pho, MD - Internal Medicine
KevinMD.com
This forum is for questions regarding Gastroenterology issues such as Acid Reflux (GERD), Barretts Esophagus, Colitis, Colon/Bowel Disorders, Crohn's Disease, Diverticulitis/Diverticulosis, Digestive Disorders, IBS, Stomach Pain.
Liver biopsy cant get straight answer
by boatlady, Jan 27, 2006 12:00AM
I need to know what this means.. and what we should do.
biopsy report reads as follows:
Cirrhosis
section shows liver with intact acinar architecture. Mild to moderate portal inflamation (inflammation) is noted within most port tracts. the inflamation (inflammation) is composed predominantly of lymphocytes and histocytes. interface changes are focally noted. lobular foci are additionally evident. focal bile duct proliferation is present. mild to marked steatosis is evidentk focal lymphoid aggregates are noted within portal tracts. there is no hemoriderosis ( iron stian reviewd) alpha 1 anti typysin globules are not indentified (Dpas stain reviewd) portal fibrosis is noted with fibrous expansion of most portal zones. Portal to protal bridging, portal central bridging and chronic hepatatis, mild to moderately active with bridging, fibrosis and evolving cirrhosis, ( grade 2-3) stage 3-4. Moderate macrovesciular steatosis. serologic evaluation for viral hepatitis is recommended.
Im getting all kinds of responses like its only a grade 1 dont worry about it but.. have concerns.. this doesnt sound good !
biopsy report reads as follows:
Cirrhosis
section shows liver with intact acinar architecture. Mild to moderate portal inflamation (inflammation) is noted within most port tracts. the inflamation (inflammation) is composed predominantly of lymphocytes and histocytes. interface changes are focally noted. lobular foci are additionally evident. focal bile duct proliferation is present. mild to marked steatosis is evidentk focal lymphoid aggregates are noted within portal tracts. there is no hemoriderosis ( iron stian reviewd) alpha 1 anti typysin globules are not indentified (Dpas stain reviewd) portal fibrosis is noted with fibrous expansion of most portal zones. Portal to protal bridging, portal central bridging and chronic hepatatis, mild to moderately active with bridging, fibrosis and evolving cirrhosis, ( grade 2-3) stage 3-4. Moderate macrovesciular steatosis. serologic evaluation for viral hepatitis is recommended.
Im getting all kinds of responses like its only a grade 1 dont worry about it but.. have concerns.. this doesnt sound good !
Doctor's Answer
by Kevin Pho, MD, Jan 28, 2006 12:00AM
, Jan 28, 2006 12:00AM
The liver biopsy does show some long-term damage, as well as inflammation. It suggests that the cirrhosis is at a mild stage. The key would be finding what is causing the damage.
Viral hepatitis would be of concern. This can be evaluated via blood tests. I would also consider obtaining an alpha-fetoprotein level. There is an association between viral hepatitis and liver cancer.
I would discuss these options with a liver specialist.
Followup with your personal physician is essential.
This answer is not intended as and does not substitute for medical advice - the information presented is for patient education only. Please see your personal physician for further evaluation of your individual case.
Kevin, M.D.
kevinmd_b
Viral hepatitis would be of concern. This can be evaluated via blood tests. I would also consider obtaining an alpha-fetoprotein level. There is an association between viral hepatitis and liver cancer.
I would discuss these options with a liver specialist.
Followup with your personal physician is essential.
This answer is not intended as and does not substitute for medical advice - the information presented is for patient education only. Please see your personal physician for further evaluation of your individual case.
Kevin, M.D.
kevinmd_b
Basically the report states that you have had long standing liver disease of a cause that hasnt been determined yet.
i have minimal fibrosis with slight portal tract imflammation
and slight fatty liver. Can anyone tell me what that means.
I was a heavy drinker for 15 years and now have stopped.
Dr. said not to worry. But i have symptoms of liver disease.
Is this because my liver is damaged. over time will this
get better. It seems the Dr. always says dont worry, they
dont want to tell you everything.