I am hoping someone might have some ideas here, because both my gastroenterologist and family Dr are out of ideas. I am a 24 year old female, and have been experiencing severe lower right abdominal pain for nearly 7 months now. I have had 2 pelvic/abdominal CT scans, a pelvic/abdominal ultrasound, colonoscopy with biopsies, and a capsule endoscopy that all came back normal. I have had 3 ESR blood tests run that all came back high and a high CRP with mild anemia, taken over the past 3 months. I have lost 15 lbs in the past month and a half, and find it very difficult to eat as I am in pain most severely after eating, though I do experience the pain with out eating as well. I have had almost one bout of diarrhea almost every day since 2004. I have no fever, though I feel feverish and chilly sometimes. I have felt very lethargic, tired, and light headed. My Drs have ruled out Crohn's, IBS, colitis, gonorrhea, syphallis, gall stones, kidney stones, bladder infection, appendicitis, and ovarian cists. My gastro is stumped and ordered another ESR and CRP to be done yesterday, and I have been told if they come back as elevated as they have been that they will consider exploratory surgery, which I really would like to avoid. If any one has any ideas of what this may be, that would be greatly appreciated, or even an idea of what they may be able to see by cutting me open, that they haven't already been able to see? Any idea/input is greatly appreciated.