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Gastroenterology  (Expert Forum)
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PPI's and H2 Drugs...
This forum is for questions regarding Gastroenterology issues such as Acid Reflux (GERD), Barretts Esophagus, Colitis, Colon/Bowel Disorders, Crohn's Disease, Diverticulitis/Diverticulosis, Digestive Disorders, IBS, Stomach Pain.

PPI's and H2 Drugs...

by djtech, Aug 07, 2002 12:00AM
Greetings,

I have tried absolutely all of the PPI drugs.  Aciphex made me VERY bloated and numb, and could not get a lower dosage as apparently they don’t make one. Protonix just plain made me feel like **** all over.  Nexium worked ok but made me feel quite nauseous. Prevacid seems to work the best of all of them probly because number one, I can take the lower 15mg tablet and so I don’t get too much bloating because of too much acid block during the day.  I do sometimes feel the stomach discomfort but do not know if it’s the prevacid or just my stomach acid stuff.  Now I have tried some of the H2 blockers.  People and the pharmacist recommended Pepcid, I tried it and was latterly wired and felt very strange.  Next I tried Zantac and it seemed ok.  A bit nauseous after first taking it but not too bad thereafter.  But when taking it RIGHT before bedtime sometimes I would get VERY strange and overly realistic nightmares.  Almost hallucinating type.  So here I am.  Have been thoroughly checked out by my gastro specialist. Endoscopy biospsies revealed nothing big.  She claimed gastritis.  I am extremely lightweight as a man and getting a lot of food in me is important but feeling the bloating feeling constantly makes it VERY difficult to keep shoveling if you catch my drift.  Any other H2's that anyone can recommend other than Zantac that has heard good things about?  I need to lick this thing before I get too damn thin.  Preferebly an H2 with VERY low if any side effects.  Thanks!

DJ
Member Comments (6)

by Lynn28, Aug 07, 2002 12:00AM
Gastritis is causing all the pain. It's a killer. I have to laugh when doctors say, "Oh, everything is fine, just a little gastritis." Gastritis is awful and extremely painful and it takes a year and a day to ever go away. Are you taking any PPI's to help heal the gastritis? I took protonix for about 8 weeks and it was the "Only" thing that helped me. At first I had bad headaches, but knew I had to ride it out in order to heal myself. It took away the burning, but not everything. I've had it now going on two years and it is awful!! How long ago were you diagnosed with it? I hope you find relief soon ;-)

-Jenn

by gregd64, Aug 07, 2002 12:00AM
I've taken prilosec and nexium but they made me feel bloated and full all the time plus headaches...  My doctor had me take 2 20mg
pills a day..  I knocked myself down to 1 pill aday in the morning and started feeling less bloated and no heartburn but still didn't feel great. Then and now I take 1 pill everyother morning and it has worked wonders for me. I also have used maalox in the past with a zantac which also worked for me. good luck.

by John W. (RPh), Aug 11, 2002 12:00AM
Sorry to hear of your misfortune!

Let's see, you've exhausted all the PPI's and 2 of the more popular H2 blockers.  All you have left is a trial of Axid (my suggestion would be the 150mg RX strength which is now available in generic).  There is a possibility of trying OTC Tagamet, but I generally do not recommend it as it has many interactions with other medicines.

If the Axid or Tagamet does not work, you are left with the old standby's like Maalox.  If you go that route, the formulation which works best is Gaviscon.

Hope this helps

John W. (RPh)

by karie, Aug 12, 2002 12:00AM
To: John Rph
Is it common for a racing heart and other bad side-effects to H2 blockers ? My pharmacisit said it is not uncommon.
Are these drugs effecting the CNS and this makes the body work harder ?
I tried Nexium but it did not help at all and after 6 weeks was taken off it. Only headaches and stomach pain on that one.
But Prevacid and Ranitidine caused chest pain and racing heart with pvc's,
For one who does not use caffeine, sugars, chocolate it was too much.
What is your impression of DGL ? I and others have posted about it here ?
Gaviscon is one I never tried months ago.

by aklap, Aug 12, 2002 12:00AM
To: karie2
You had asked about DGL.  I been taking DGL for a little over a month.  I think it helps. I'm finally (sort of) getting used to the taste. I was taking 2 150mg Ranitidine a day and an occasional 20mg Nexium if it gets really out of hand - after about 2-3 weeks of DGL, I started cutting back on Ranitidine.  I think I was down to 2 75mg a day.  But...I believe a recent Nexium triggered a gout attack.  So I took some Vioxx to deal with that - which in turn is sending my stomach into a fizz :(  Kind of a nasty circle. Volleyball ends in 2 weeks so I can stop the vioxx - hopefully things will settle back down.  Has anyone else had problems w/ Nexium & gout??  I have trouble w/ gout anyway...I believe that's what got my stomach into the mess it's in today - all the anti-inflams.  It was course of prednesone & vioxx that sent me over the edge.  Is there a "kinder, gentler" anti-inflam??

Al

by karie, Aug 13, 2002 12:00AM
Dr. Weil says www.drweil.com That taking DGL is a great healer But not with PPI's or H2's.
I personally don't  have gout But 2 relatives do and they were told to quit alcohol and watch diet.
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