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Gastroenterology  (Expert Forum)
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Re: Undiagnosed liver problems
This forum is for questions regarding Gastroenterology issues such as Acid Reflux (GERD), Barretts Esophagus, Colitis, Colon/Bowel Disorders, Crohn's Disease, Diverticulitis/Diverticulosis, Digestive Disorders, IBS, Stomach Pain.

Re: Undiagnosed liver problems

by HFHSM.D.-rf, Jan 01, 1995 12:00AM
Posted By HFHSM.D.-rf on June 14, 1998 at 16:53:23:

In Reply to: Undiagnosed liver problems posted by Maureen on June 05, 1998 at 02:45:22:






I have been diagnosed with fibromyalgia, gilberts syndrome,trigeminal neuralgia, ulcerative esophagitis, and colitis, to name just a few.  I currently have lab tests of ANA 1:640  ACE level 43, ESR 30, ANFA  <10.  My LFT's of alkaline phosphatase and GGT are always abnormal and have been so for over 15 years. My doctors are baffled, I have had surgery for dislocating joints, hernias and incompetent cervix during pregnancy.  I currently get large blood blisters, mainly in my mouth and have numerous petechiae and spider naevus all over my body. The fibromyalgia lays me low, but I do not believe that I  am just "unlucky" and am currently researching immune disorders to try and get some answers. Do you have any ideas or suggestions, my doctor says that pathology results prove there is something wrong, but can't come up with a definitive diagnosis.
____


Dear Maureen,
I read your e-mail with great interest and I have several thoughts regarding your gastrointestinal and liver problems.  The Gilbert's Disease is not the cause of your elevated liver tests.  The ulcerative esophagitis is most likely the result of acid reflux into your esophagus and does not represent a manifestation of autoimmune disease.  If you have been prescribed corticosteroids, it is possible that your esophagitis is the result of candida infection.  This possibility was probably excluded when you had the endoscopy that diagnosed the esophagitis.
I am interested in your diagnosis of colitis.  Do you have additional details regarding the specific nature of the disease process.  Colitis is a pathological term that means inflammation of the colon.  However, in clinical jargon the word colitis has taken on a broader meaning and is now used to refer to functional as well as organic diseases of the colon.  Again, it is possible that there is no connection between the colon and your other autoimmune problems.
Finally, your elevated alkaline phosphatase and GGT require additional evaluation.  Have you had an ultrasound of the liver?  Although the ultrasound test will provide some useful information, it will probably not provide a definite answer.  It may be appropriate to have a liver biopsy to make a specific diagnosis of the cause of your increased liver tests.
This information is provided for educational purposes only.  always consult your physician for specific medical problems.
HFHSM.D.-rf
*keywords: elevated liver tests, esophagitis, colitis
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