Hello - thanks for asking your question.
I cannot diagnose you over the internet - you should absolutely follow this up with your personal physician.
Here are some possibilities for chronic nausea and vomiting.
Rumination
The rumination syndrome is increasingly recognized among adults of normal mental capacity. It is included in the differential diagnosis, but differs from vomiting. The behavior consists of daily, effortless regurgitation of undigested food within minutes of starting or completing ingestion of a meal.
Gastroesophageal reflux disease
The most common symptoms of gastroesophageal reflux disease (GERD) are heartburn (or pyrosis), regurgitation, and dysphagia. Patients typically regurgitate acidic material mixed with small amounts of undigested food.
Eosinophilic gastroenteritis
Benign eosinophilic infiltration of the gut is a rare disorder which can occur anywhere from the esophagus to the colon, causing symptoms dependent upon the area and tissue layer of bowel involved. Gastric mucosal disease is typically associated with nausea and vomiting.
Viral gastroparesis
Approximately 50 percent of patients with chronic idiopathic nausea and vomiting evaluated in referral centers have gastroparesis. A viral etiology was suggested in these patients and in other series when there was an acute onset of nausea and vomiting with other features of a viral illness (fever, myalgia, diarrhea, fatigue, or abdominal cramping).
Chronic idiopathic intestinal pseudo-obstruction
This is a syndrome that suggests mechanical bowel obstruction of the small or large bowel in the absence of an anatomic lesion that obstructs the flow of intestinal contents.
Cyclic vomiting syndrome
Cyclic vomiting syndrome is a disorder characterized by repeated episodes of nausea and vomiting that last for hours to days separated by symptom-free periods of variable length. In adults, the disorder has been described as consisting of episodes of nausea and vomiting lasting for three to six days in a patient-specific stereotypic pattern.
There are many other causes of nausea and vomiting including the following:
- acute non-GI infections (pyelonephritis, pneumonia)
- hepatobiliary disease
- pancreatic disease
- peptic disease of the esophagus, stomach, or duodenum
- gastric or ovarian carcinoma
- CNS diseases - infections, tumors, multiple sclerosis
- metabolic disturbances - diabetes, adrenal insufficiency,
hypercalcemia, pregnancy
You seem to have undergone a comprehensive battery of tests. I would strongly suggest that you follow this up with your personal physician or gastroenterologist.
I stress that this answer is not intended as and does not substitute for medical advice - please see your personal physician for further evaluation of your individual case.
Thanks,
Kevin, M.D.