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Gastroenterology  (Expert Forum)
 | 
Yeastinfection
Answered by
Kevin Pho, MD - Internal Medicine
KevinMD.com
This forum is for questions regarding Gastroenterology issues such as Acid Reflux (GERD), Barretts Esophagus, Colitis, Colon/Bowel Disorders, Crohn's Disease, Diverticulitis/Diverticulosis, Digestive Disorders, IBS, Stomach Pain.

Yeastinfection

by Gerardina, Mar 13, 2004 12:00AM
Last year I have posted a question about my symptoms . One of the advices were to think of a yeast infection. I have read a few articles on candida. I must say that I do recognise a lot of the symptoms described. Is it possible that the yeast has been settling in my mucous lining throughout my body? Possibly for the last ten years.
Also in one of the articles they mentioned a triple medication therapy. Could you give me some information on that so I could take that to my GP.Which medications are currently used , what sideeffects to watch for etc.
I am already on a fat and protein diet as I am not able to eat carbohydrates very well and it is getting worse.
Can the candida also be the cause of those awfull headaches I get about twelve to eighteen hours after eating a light carbohydrate meal?I need all the help I can get to convince my GP.

by Kevin Pho, MD, Mar 15, 2004 12:00AM
The best way to diagnose the presence of Candida would be to demonstrate it during an endoscopy (either upper or lower endoscopy) or during a stool sample that is sent off for a fungal culture.  

As for treatments, it can involve oral antifungal agents (i.e. Fluconazole).  However, there are no consensus studies suggesting improvement after the eradiction of Candida.  I would look for other etiologies (i.e. malabsorption, bacterial overgrowth etc.), before settling on Candida as a diagnosis.  

I am unaware of Candida causing headaches after eating a light carbohydrate meal.  

Followup with your personal physician is essential.

This answer is not intended as and does not substitute for medical advice - the information presented is for patient education only. Please see your personal physician for further evaluation of your individual case.

Thanks,
Kevin, M.D.
Member Comments (7)

by PAJ, Mar 15, 2004 12:00AM
Yeast does not always show on endoscopy , the white deposits seen with yeast overgrowth are a relatively superficial infection and again relatively easy to cure with fluconazole in fact the drug is dramatic in eradicating thrush. What does show on endoscopy is red patches , it’s thought as a result of invasion of the tissues by the organism. [see below] Stool cultures are very unreliable ,statistically four need to be carried out before the results are considered  viable ,there are much better tests available .
http://www.aal.xohost.com/candidacontent.htm
Other tests notably organic acid testing or metabolic profiling As detailed by Great plains laboratorys These tests have a
proven record ,as with all the tests getting the doctors to accept the significance of the result is the problem here.

http://www.greatplainslaboratory.com/yeast.html

                  The good doctor tells us there are no consensus studies suggesting improvement after the eradication of Candida, that’s because the medical profession do not recognise yeast infections in the community ,they steadfastly ignore the problem, very few studies have been carried out.  I can tell you that there are many cures following treatment. I relate to your headache its akin to a migrain which are known to be of gut origin   One avenue to explore for a diagnosis is a trial on antifungal drugs! In particular Nystatin it’s a very safe drug and if your problem is yeast will dramatically subdue your symptoms although it does not offer a cure ,[ 8 million units per day for two weeks] the risks are minimal with the possible benefits enormous.

With long term infection , co-infections are a certainty , the condition develops into a dysbiosis that is several pathogens colonise the gut.

http://www.scienceinafrica.co.za/2002/march/dysbiosis.htm the down regulation of the immune system ,leaves you wide open to serious opportunistic pathogens. PMID: 10865902 [MEDLINE]
See also Medline 11098625


Department of Molecular and Cell Biology, Institute of Medical Sciences, University of Aberdeen, AB25 2ZD, Aberdeen, UK. n.***@****

Many fungal pathogens undergo morphological transformations during host invasion. However, the significance of this for fungal pathogenesis is not clear. Both yeast and hyphal cells have properties well suited to tissue invasion and evasion of the immune system. However, molecular control circuits that regulate morphogenesis also regulate the expression of other virulence traits. To establish the extent to which morphogenesis impacts on pathogenesis, it is necessary to characterise the morphology of the fungus at different stages and locations during the natural history of a disease and to untangle how gene expression is modulated at these stages. This review considers the role of morphogenesis in fungal infection and argues that no simple, universal relationship can be drawn between morphology and the invasive potential of a fungus.

Publication Types:
· Review
· Review, Tutorial

PMID: 12160854 [PubMed - indexed for MEDLINE]

Is it possible for yeast to become systemic?
Candida Albicans has two separate shapes and forms. It exists and breeds in these two states in the gut and has the ability to change from the yeast like organism to the mycelial [fungal form].The yeast like state is non invasive and the fungal state produces hyphe (root like structures) which can bore their way through the mucous membranes of the intestines. [Medline 12160854]
The intestines are designed to retain the natural waste and toxins of the body prior to elimination. Digestive enzymes and protective processes in the gut attempt to recognise and destroy harmful bacteria and to render allergens, chemicals, additives, pesticides, herbicides, hormones etc in food, harmless to the rest of the body. When Candida overgrowth is present the ph/alkaline balance in the gut is also compromised.
If the organism penetrates and damages the walls (mucous membrane) of the intestines, those retained toxins [molecules] are then able to penetrate the rest of the body via the circulatory system. This is a recognised condition "known as "Leaky Gut Syndrome".
If the digestive system is compromised in this way, undigested foods are also able to enter directly into the body via the blood stream and the body will react as it would to anything else found in the blood stream, which should not be there. In other words, it will see the allergens in foods or toxins as an alien/enemy attacking the immune system…and will fight to rid the attacker from the body. This may be expressed as an "allergic" reaction.
It is thought that Candida via this rout can enter the blood stream. Also with virulent Candida Albicans its thought that intestinal lesions provide the mechanism for dissemination via the lymphatic system. [Medline 10834995]
Once Candida is disseminated it can in the same way it caused inflammation in the gut, have the ability to create inflammation throughout the whole body. The brain, muscles, joints, nervous system and every other organ and structure will be assaulted by the yeast.
This assault will generally debilitate the whole body. Because the body always fights and tries to rectify problems unaided, it can only accommodate the situation for so long. This stage may well be the first time that the person becomes aware of any problem. How many times do we hear - I've always eaten this/that or done this/that and it's never been a problem before? So the mistake is made that it was a particular food or something in a new environment which has caused the problem now, when it fact it has been building up over a period of time. It is only when the body finally gives up and expresses an "allergic reaction" that we become aware or take notice.
The above is just a overview ,if you have questions don’t hesitate to post . Oh forgot, the triple therapy is in Dr Crantons site in one of my posts below

by yoshi, Mar 16, 2004 12:00AM
severe yeast infection is not that common in developed countries,unless you have been taking antibiotics for a long time.live in area where there is a lot of humidity,fungus in old houses with old airduct.
if you have yeast infection,you would crave for starchy food,sugar.
i dont know what triple medication you are referring to,prepac which is used to treat h pylori consist of 2 antibiotics and prevacid,but this is not for yeast infection.
most people take yogurt with that good bacteria,take pills called yeast fighter and primal defense which you can find in health food stores.
yeast/fungal infection would make you feel drowsy,crave for carbohydrates and sugar and bloated stomach .
as for headache,i know some people cannot handle a high protein diet,they need a balanced diet with some green and some carbo.dont forget your brain is the big user of sugar.

by PAJ, Mar 16, 2004 12:00AM
severe yeast infection is not that common in developed countries, unless you have been taking antibiotics for a long time. live in area where there is a lot of humidity, fungus in old houses with old airduct …..What a laugh, not common that is unless you’ve taken antibiotics for a long time!!! Nearly there , do you know a how many people have taken aBx’s for lengthy period? Houses with mould!! A prerequisite for yeast?????


.
if you have yeast infection you would crave for starchy food,  sugar……. Very true as the infection is progressive with time a host of other symptoms.


i dont know what triple medication you are referring to, prepac which is used to treat h pylori consist of 2 antibiotics and prevacid, but this is not for yeast infection. You don’t say!!! Well well ABX’s not good for yeast ,fancy that.


most people take yogurt with that good bacteria, take pills called yeast fighter and primal defense which you can find in health food stores……..  Well well again !! is that all it takes ? better tell Dr Cranton he’s currently sticking his neck out prescribing triple antifungal therapy ,hell be relieved to hear that a few naturals will do the trick.

yeast/fungal infection would make you feel drowsy, crave for carbohydrates and sugar and bloated stomach .   Very true again ,you stated that before didn’t you?

as for headache,i know some people cannot handle a high protein diet,they need a balanced diet with some green and some carbo.dont forget your brain is the big user of sugar……. I fail to see the connection, What’s the relevance of the brain being a big user of energy .


I make a point of backing my opinions with credible scientific evidence , I recommend it ,because if you just talk from the top of your head you run the risk of being regarded as a dork whose got hold of a computer terminal ,, so if you don’t mind back up your observations with credible evidence or relevant experience.
Anyway I thought you were fed up with my yeast posts.

Here’s one for you .. why are the so called wonder drugs Statins so successful against a wide range of illnesses.

Is it
a…….because they work reducing cholesterol  and that somehow relieves and sometimes cures a wide range of illnesses.

Or B ….because they were first developed as an antifungal and as such work against long term simmering fugal infections ,contracted as a result of consuming sugar on a staggering scale altering the gut flora , gut flora that is further altered by the widespread overuse of antibiotics.



Answer B  any comments?

by tessa0825, Mar 16, 2004 12:00AM
To: PAJ
Do you not realize that this is an open forum and as that being the case, everyone is entitled to their opinion ?....It is not  very wise (or intelligent) to come on an open board and critisize to the point of name calling....You should offer an apology and Med-Help should remove your post..

by yoshi, Mar 16, 2004 12:00AM
i am posting my comments to the author of this thread,i do not realise PAJ owns the board??
i dont know what triple treatment she is referring to,i am just quoting what i know,is there one for yeast infection,if there is,then it is good to know.

by ohio2, Mar 23, 2004 12:00AM
I have had acid reflux and gastritis for over a year now. I have used antacids, H2 blockers, and all the PPIs (protonix, prevacid, and now nexium). I continued to have off-and-on bouts with heartburn and abdominal pain throughout this last year. I even had an upper GI and an endoscopy in January which was negative for ulcers and negative for h. pylori.

However, just last week I went to the doctor for a different problem. I had a pinkish rash on my shoulder, neck, and tailbone (I had had the rash once before years ago). Dr. said it was a fungal skin infection and prescribed Diflucan. Since taking the Diflucan, my skin cleared immediately, but surprisingly, all my heartburn and abdominal symptoms have disappeared.

I am curious as to whether my GERD and abdominal pain were caused by fungus. I have read that candida can cause gastritis in immunosuppressed individuals (I am not immunosuppressed, very healthy aside from GERD). If fungus can cause GERD and gastritis, why did no doctor of mine ever check or even consider fungal infection?

by JaSam, Mar 25, 2004 12:00AM
I have been through triple therapy for eradication of HP bacteria just a month ago. After I finished therapy I started having some more problems with my stomach that seem to calmed down now. The only thing that still bothers me is the red skin around my anus that is at the time very itchy. Sometime it is very red and sometime just pinkish. It goes almost from my scrotum to my tailbone. This thing started just after I finished HP Pac therapy. Could this be something related to unbalanced stomach flora caused by antibiotics.

by met_tech, Jun 30, 2008 07:17PM
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