c-dif treatment

My father had a colectomy with colostomy mid-May due to a severe infection caused by diverticulitis. While recovering from surgery in a rehabilitation facility, he was diagnosed with c-dif. He was prescribed Flagyl and Vancomycin. However, he had an allergic reaction to the Vanco on his first day of treatment and it was immediately dc'd.

He cont'd on Flagyl for 14 days. However, when they received the results of the stool culture, he was told today he still has c-dif. They are starting him on another round of Flagyl for 14 days. I have read that repeated rounds of Flagyl are not typically effective without Vancomycin.  I am really concerned as this is the second major surgery my father has been through in the past 6 months. He is not in good health.

[CalGal]

DEgirl, please check with www.cdiffsupport.org. They're a good group with a lot of good suggestions and experience with C. diff.

In addition, you may want to glance at and article on Medscape.com. You'd have to sign in, but they've got good information on a lot of medical subjects. http://www.medscape.com/viewarticle/704351 - “Tigecycline Effective for Severe Refractory C. Difficile Infection.”

[DEgirl]

Thanks for your recommendations. I will definitely check the sources you mentioned.