In general, the more common and first-line drug is Flagyl (metronidazole). If that drug fails to be effective or cannot be tolerated then Vancocin (vancomycin) is commonly prescribed. However, vanco is expensive and is considered the drug of last resort. At the present time there are no other 'main line' drugs - to my knowledge - that are 'accepted' defense against C. diff. There are antibiotics that are being tried.
If a person is infected and being treated in a home setting, hygiene is very important. C. diff produces spores when attacked by antibiotics, and the spores can live in the open air or on surfaces for fairly long periods of time. Normal disinfectants have been shown ineffective against the spores, so bleach solutions need to be used to disinfect surfaces and a lot of hand washing needs to be used to make sure that when you kill off the C. diff in a patient the spores that can 're-infect' or infect are also killed off.
A person who is told they have C. diff really needs to be working with a doc who thoroughly understands the treatment of C. diff, and that person may be an infectious disease doc.
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