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elevated Creatine Kinsae

-healthy 37 yr old man with shoulder pain in left shoulder for the past 15 years that comes and goes. First noticed it while lifting weights back in college.(history of arthritis in the family. mother has arthritis in the knees and shoulder. Her mother had arthritis severely in joints as well).
I also recently had a swollen knee about 3 days after doing squats in the gym. This was new and the knee stayed swollen for about 2 weeks!  This was 2 months ago. Since then the knee has hurt on and off.
Took a blood test two weeks ago. diagnosed with herpes simplex 1 and 2.
Also had a slightly high AST level at 41.  The normal AST range was 10-40.  I had a normal ALT level at 30. The normal ALT range was 9-60.  And my Creatine Kinase level was high at 1085. The normal Creatine Kinase level was less than 200.
Could the bad shoulder and the unexplainable swollen knee have something to do with an elevated Creatine Kinase and slightly elevated AST level?
I drink beer maybe 2 or 3 times a week at the most.  Have drinked socially for the past 10 yrs.
My father was a heavy drinker and died at age 53 with a bad liver from drinking profusely for 40 yrs. I dont drink nearly that much so i really dont think its a liver issue with me. I think its more of a muscle that is leaking enzymes.
Does the high enzyme level have anything at all to do with the recent diagnosis of herpes?
I am taking another blood test later this week to determine if the CK levels have gone down.
By the way, before the blood test I had not really worked out with weights or did any streneous excercise for 4 or 5 weeks previous, and even then it wasnt any heavy lifting or any strenuous excercise.
Oh, the blood test also showed "not reactive for any of the hepatitis' and for hiv.
thanks. i would gladly appreciate any input..
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Avatar universal
Thanks.  I am going to see a knee specialist this Friday.  
By the way, i failed to mention that i've had sore knees on and off for years also except this one time after doing deep knee bends the knee actually swole up very big for a couple of weeks. thats the first time that happend. But prior, my knee had given me problems over the years since i was 11 or 12 yrs old.  One time when playing in a 6th grade basketball game the same knee went out on me and i could barely walk for a week.  I also played little league back catcher for 3 yrs and i always felt slight knee pain even back then and that was 25 yrs ago!!!

The left shoulder problem as i said has been going on for years also. I havent been able to touch the back of my right shoulder without pain and discomfort, reaching across the front of my body with my left hand, for about 10 yrs.
My cholesterol levels were fine and in the normal ranges.  

So elevated Creatine Kinase is associated with herpes. wow. i've read a ton of stuff and i dont think i've come across that one..
is there a website that explains that?
Do you think a throrough analysis of my knee/knees would shed light on the elevated Creatine levels?
I have read that when muscles leak, they can leak Creatine Kinase into the blood stream, but i didnt know the knee had any skeletal muscle. I thoughtBOTH the shoulder and the knee were merely joints?
Helpful - 0
Avatar universal
hi , eric


Creatinine Kinase (CK, CPK) is an enzyme found primarily in the heart and skeletal muscles, and to a lesser extent in the brain. Significant injury to any of these structures will lead to a measurable increase in CK levels. Causes  of elevation include Myocardial infarction ,Crushing muscular trauma , Any cardiac or muscle disease, but not myesthenia gravis or multiple sclerosis , Brain injury , Hypothyroidism ,Hypokalemia .
in your case elevated is moslty due to shoulder and knee trama and will take some time to come down siince once elevated, CK remains elevated for several days, if the injury is acute.  
If there is on-going injury, the CK will remain elevated indefinitely
elevated CK has also been found in herpes infection.
Also ur AST is only slightly high could be high due to alchol intake and skeletal trama
Also have u been on any medications lately ? wht abt cholesterol ?

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