extensive intestinal metaplasia

[helpme778]

Hi I am a 33 year old female and I was diagnosed with extensive intestinal metaplasia. Can someone please help me? I did an endoscopy in Nov 2010 and found out that I have extensive intestinal metaplasia. Is this reversible? The doctor said that i don't have H Peliori virus.  My question is 1) what could have possibly caused it 2) is this reversible? if it is, what should I eat and what medication should I be on? 3) I am really scared that this will turn in to stomac cancer. I heard that after 6 monhts of endoscopy, it is possible that this could turn into stomach cancer. 4) lastly, what should i do in terms of eating and diet? I don't want to worsen this situation. Should I eat a lot of antioxidants?

please help me. I don't know what to do..

ann

[Faisalfarooq]

i recently removed my gallbladder.. the biopsy report shows extensive matapalsia of pyloric gland lining. did it turn to the cancer?what are the possible treatments for that?

it will be your to kindness for me to explain

[gullane]

You need to find out the full picture.first there are three types of Metaplacia.
These are complete Metaplacia and non complete which is divided in two sub groups called type 2 and type 3.The complete type is considered less serious than the non compete type.You need to have your stomach checked out and
also establish exactly what type you had in your gallbladder.

[sansgallbladder]

I am going through EXACTLY what you went through. My understanding is that the fact that we now do not have our gallbladders that is what eliminates our risk (cancer of gallbladder). My surgeon also told me that it is nothing to worry about. I can't help but worry that if there was intestinal metaplasia in my gallbladder what's to say it's not somewhere else in my digestive system? I am going to seek info from my family doctor.

[d4444818]

Hello I just recently underwent a gallbladder cholecystectomy and when I went  for my check up with the surgeon, he told me that the pathologist found focal gastric intestinal metaplasia, but didn't give me any kind of details on it and told me not to worry.  he didn't even know what it was he said it wasn't in his field of work, so I have been trying to look it up on the internet but everything I see is talking about cancer so that leaves me to worry. I need to know what steps do I take now, is the focal gastric intestinal metaplasia gone now because of the removal of the gallbladder or should I get my other organs checked also??????

[Idas]

Your symptoms are very similar to mine. I too have chronic gastritis, intestinal metaplasia, and no H pylori.  My doctor gave me very little information.  He said the metaplasia will not go away but he feels should not cause any problems. That is not good enough for me.   Nothing helps my acid reflux - I have tried all medications, lost weight, raised my bed, and the doctor just ignors that.  I think I have bile reflux which would make sense because these meds do not work on bile reflux and bile reflux causes intestinal metaplasia from what I read.  I asked my doctor the same questions you did and got no answers.  My sister died of stomach cancer so I am scared.  I am going for a second opinion and hope I can get some of my questions answered.  If you learn anything, please let me know and I will do the same.

[Idas]

Your symptoms are very similar to mine. I too have chronic gastritis, intestinal metaplasia, and no H pylori.  My doctor gave me very little information.  He said the metaplasia will not go away but he feels should not cause any problems. That is not good enough for me.   Nothing helps my acid reflux - I have tried all medications, lost weight, raised my bed, and the doctor just ignors that.  I think I have bile reflux which would make sense because these meds do not work on bile reflux and bile reflux causes intestinal metaplasia from what I read.  I asked my doctor the same questions you did and got no answers.  My sister died of stomach cancer so I am scared.  I am going for a second opinion and hope I can get some of my questions answered.  If you learn anything, please let me know and I will do the same.

[Monhegun]

Hi, I was diagnosed of gastric antral type mucosa with mild chronic gastritis, focal intestinal metaplasia (negative for dysplasia) and junctional glandular mucosa with mild chronic inflammation.  I feel kind of burning around my chest especially in the middle of the night when my stomach is empty.  Sometimes, the pain is even radiated to my upper back and shoulder blades.  My doctor said that I have acid reflux and prescribed me "Dexilant 60mg" once daily.  I took it for almost 2 weeks.  Somtimes it works but sometimes it doesn't (because I still wake up in the middle of the night due to back pain caused by excessive acid)  Can mild chronic gastritis and inflammation of junction glandular mucosa be cured?  Per my endoscopy report, giemsa stain is negative for H. Pylori.  If my chronic gastritis is not caused by H. Pylori, what other causes will there be?  I was so worried that focal intestinal metaplasia will developed into cancer, how can I prevent it?  Also, if my acid reflux is cured, does it mean that chronic gastritis will also be cured?  I asked my doctor and she said that it's hard to find the cause of the gastritis.  Should I go to the hospital to request test for autoimmune gastritis and gastrin level test.

I was worried for a while.  Please help and advise.

Thanks

[stdinfo]

The test for bile reflux is more complicated, but you should talk to your Dr about doing tests and finding out what the underlying cause is

[stdinfo]

Hi. I'm a researcher on gastric cancer, and just to note I'm a PhD, not an MD, and I'm just a member on this forum (not a moderator), but I could give you my two cents.

Ask your Dr about "autoimmune atrophic gastritis" in which case your acid-secreting (parietal cells) or pepsinogen-secretion (chief cells) are attacked by your own immune system. This leads to high gastrin levels, which could lead to intestinal metaplasia.  

If I was you, at this stage I would 1) discuss with my Dr getting tested for autoimmune gastritis (it's a blood test for antibodies against parietal and chief cells), BUT more importantly 2) ask my Dr to measure your gastrin levels.  If your gastrin levels are high, this could give some clue as to what might be causing your condition. These are fairly quick tests, but at the same time you should discuss other possibilities for causes with your Dr at the same time.

[CalGal]

The most common type of intestinal-type metaplasia is due to H. pylori. The other types seem to be correlated to irradiation, atrophic gastritis, bile reflux, genetic links, lack of vitamin C and cigarette smoking  from what I understand.

Sit down with your doc and discuss this. Any form of medication would be related to what the specific cause turns out to be.