. I had been applying neosporin for a while and then decided to purchase caldesene baby powder. That seems to be working a little better however I am still very itchy and my crack is still pretty red. I have also been experiencing some intense stinging/stabbing pain during bowel movements resulting in bright red blood on the toilet paper (been going on for 1 ½ weeks). Here are some of my theories of what it could be. I have narrowed it down to HIV