Hello - thanks for asking your question.
Pain after
cholecystectomyGallbladder removal is a known entity (please see my previous answers regarding Post-cholecystectomy syndrome).
If there are stones remaining in the duct, a procedure known as an ERCP is commonly done by a gastroenterologist. This will identify and remove stones in the duct. If, after a complete evaluation (including an ERCP with sphincterotomy), a patient continues to have debilitating, intermittent RUQ pain, and no diagnosis is found, the procedure of choice after a normal exploratory laparotomy is a transduodenal sphincteroplasty.
Here are some adverse effects of PegInterferon from the Drug Information Handbook:
"ADVERSE REACTIONS >10% : Central nervous system: Headache (56%), fatigue (52%), depression (16% to 29%), anxiety/emotional liability/irritability (28%), insomnia (23%), fever (22%), dizziness (12%), impaired concentration (5% to 12%), pain (12%) Dermatologic: Alopecia (22%), pruritus (12%), dry skin (11%) Gastrointestinal: Nausea (26%), anorexia (20%), diarrhea (18%), abdominal pain (15%), weight loss (11%) Local: Injection site inflammation/reaction (47%), Neuromuscular & skeletal: Musculoskeletal pain (56%), myalgia (38% to 42%), rigors (23% to 45%) Respiratory: Epistaxis (14%), nasopharyngitis (11%) Miscellaneous: Flu-like syndrome (46%), viral infection (11%)"
As you can see, abdominal pain is a potential adverse effect. However, there are plenty of other reasons for RUQ pain and this should be explored with your personal physician. I strongly suggest followup.
I stress that this answer is not intended as and does not substitute for medical advice - please see your personal physician for further evaluation of your individual case.
Thanks,
Kevin, M.D.
Lori