Hello - thanks for asking your questions.
1) There are several tumor markers that are used for surveillence of cancers. However, except for the
PSAPsa
Psa blood test (and this is controversial), none of them are advocated for wide use for screening in the general population.
Colon cancer - Carcinoembryonic Antigen (CEA) - This is used to monitor treatment in those already diagnosed with colon cancer. Increased CEA levels can also be found in cirrhosis and peptic ulcers.
Liver and Ovarian cancer - Alpha-feto protein (AFP), CA 125 (in ovarian cacner) - Again, there are disease other than cancers that can raise levels of this.
Prostate Cancer - Prostate-specific antigen
Regarding the erythrocyte count, a more common presentation of colon cancer would simply be iron-deficiency anemia. Any adult with unexplained iron-deficiency anemia should be evaluated with a colonoscopy.
Please note that blood tests are not widely used for screening. In the case of colon cancer, colonoscopy is still the standard for screening.
2) Without examining you, I do not know what is causing your pain. A cyst may be possible. If your BE test was negative, I would suggest either a colonoscopy or an abdominal CT scan as the next diagnostic step.
3) There is nothing 100%, but here are some tests that are used to diagnose suspected cancer:
colon cancer - colonoscopy
ovarian cancer - pelvic ultrasound
lung cancer - cxr/chest CT
pancreatic cancer - abdominal CT scan
liver cancer - ultrasound/CT scan
renal cell cancer - ultrasound/CT scan
I would strongly suggest discussing these issues with your personal physician or gastroenterologist.
I stress that this answer is not intended as and does not substitute for medical advice - please see your personal physician for further evaluation of your individual case.
Thanks,
Kevin, M.D.