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How soon should I have another colonoscopy? I had a 3cm polyp removed from the rectum. It only invaded the mucosa, not the submucosa,and not the muscularis layer. The pathology report diagnosis is as follows: Large villous adenoma with focalFocal neurological deficits high-grade dysplasia. negative for malignancyHyperpigmentation w/malignancy Malignancy (see comments) COMMENTS: Due to fragmentation, integrity of margin can not be evaluated. correlation would be helpful. How close am I to having colorectalColon cancer Colorectal polyps cancer? Should I be concerned.