The larger the Number, ie 25 gauge vs. 21 gauge the SMALLER the lumen or "barrel width" of the needle tube. Think of it as a pipe and the distance that measures across the diameter of the opening,,,the larger that width, the greater amount of a substance can pass through. In needle gauges #'s, however....think of opposites: # 19 gauge is "wider" than a # 25 gauge, which is much smaller, used for subcutaneous injections such as insulin. A # 23 gauge needle is the standard for an IM injection, but it's lumen is narrower than say a #21 or a #19. A #23 is usually used to draw blood, unless the patient is a difficult stick, in that case, the "butterfly" a # 25, will be used, usually on the hand. A liquid medication such as B-12 or testosterone is a much thicker medication, so sometimes a smaller "#" on the gauge is indicated, especially condsidering the area where you are shooting....A deep IM injection on the glut area (buttock) on a person that has a bigger layer of body fat may 1) require a longer needle to reach the muscle and 2) a smaller gauge needle which is a "wider" needle" ie gauge # 21 ) to get the med into the system.
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