Genetic Disorders Expert Forum
Lupus and HLA B27
About This Forum:

Questions in the Genetics Forum are being answered by medical professionals and experts. This forum is for questions and support regarding a person’s predisposition to a variety of medical conditions such as Ashkenazi Jewish Diseases, Bleeding Disorders, Blood Clotting Disorders, Cancer Genetics and Hereditary Cancer Syndromes, Chromosome Abnormalities, Congenital Birth Defects, Cystic Fibrosis, Family History, Fragile X Syndrome, Infertility, Newborn Screening, Rare Genetic Disorders, Prenatal Screening and Testing.

Font Size:
A
A
A
Background:
Blank
Blank
Blank
This expert forum is not accepting new questions. Please post your question in one of our medical support communities.
Avatar universal
Lupus and HLA B27
Is there any research that links lupus to being an HLA B27?
Discussion is closed
Cancel
3 Answers
Page 1 of 1
886824 tn?1253740254
HLA B27 has been primarily associated with susceptibility to develop spondyloarthropathies, which are chronic, inflammatory joint diseases. Spondyloarthropathies include ankylosing spondylitis (AS), a subset of psoriatic arthritis, reactive arthritis, arthritis associated with inflammatory bowel disease, and undifferentiated spondyloarthropathy.
Discussion is closed
Cancel
Avatar universal
I knew all that. But there are over 100 different disorders now being linked to HLA B27, is Lupus one of them. Psoriatic arthritis and inflammatory bowel disease are now considered autoimmune disorders. There have been numerous diseases added recently to the suspected list of autoimmune disorders such as Schizophrenia. In the past HLA B27 was not correlated to autoimmunity but now obviously it is. I am positive for HLA B27 and have Lupus. My sister has autoimmune thyroid disorder and psoriatic arthritis. A brother has ulcerative colitis and years ago had Schizophrenia. I suspect a genetic HLA B27 connection to Lupus but as yet no one seems to have any knowledge.
Discussion is closed
Cancel
Avatar universal
A related discussion, HLA-B27, associated conditions, and the Lupus Connection was started.
Discussion is closed
Cancel
A
A
Blank
Weight Tracker
Weight Tracker
Start Tracking Now